SCHEMBL29323762

SCHEMBL29323762

C=Cc1ccc(C(=O)OCCS(=O)(=O)c2ccncc2)cc1

nearest known ligand 0.50

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
SNCA P37840 1/20 0.50
ALDH1A1 P00352 4/20 0.41
TDP1 Q9NUW8 2/20 0.39
KDM4E B2RXH2 5/20 0.37
LMNA P02545 1/20 0.37
MMP1 P03956 1/20 0.36
L3MBTL1 Q9Y468 1/20 0.36
KMT2A Q03164 2/20 0.35
GLA P06280 1/20 0.35
TSHR P16473 1/20 0.35
RAB9A P51151 1/20 0.35
AGTR1 P30556 1/20 0.35
MEN1 O00255 1/20 0.34
MAPT P10636 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29323769 0.87 TDP1 (0.44) ALDH1A1TDP1LMNARAB9AMAPT
SCHEMBL29323767 0.85 KMT2A (0.44) ALDH1A1TDP1KMT2A
SCHEMBL29323772 0.85 ALDH1A1 (0.43) ALDH1A1TDP1LMNAL3MBTL1KMT2A
SCHEMBL29323779 0.79 TSHR (0.43) SNCAALDH1A1TDP1LMNATSHR
SCHEMBL12376769 0.79 TDP1 (0.43) SNCAALDH1A1TDP1LMNAL3MBTL1
SCHEMBL29323696 0.78 THRB (0.42) SNCAALDH1A1LMNAMMP1KMT2A
SCHEMBL29323796 0.78 ALDH1A1 (0.49) ALDH1A1TDP1KDM4ELMNAKMT2A
SCHEMBL26417020 0.77 SNCA (0.49) SNCAALDH1A1TDP1LMNAKMT2A
SCHEMBL29110130 0.74 SNCA (0.48) SNCAALDH1A1TDP1LMNAL3MBTL1
SCHEMBL26417026 0.74 TDP1 (0.58) SNCAALDH1A1TDP1LMNATSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20240241440-A1 POLYMER, PHOTORESIST COMPOSITIONS INCLUDING THE SAME, AND PATTERN FORMATION METHODS U.S. BANK TRUST COMPANY, NATIONAL ASSOCIATION, AS NOTES COLLATERAL AGENT 2024-07-18 US disclosed
US-20240241440-A1 POLYMER, PHOTORESIST COMPOSITIONS INCLUDING THE SAME, AND PATTERN FORMATION METHODS U.S. BANK TRUST COMPANY, NATIONAL ASSOCIATION, AS NOTES COLLATERAL AGENT 2024-07-18 US disclosed