Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.45 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.42 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.42 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.42 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.42 |
| ▸ | ACKR3 | P25106 | 2/20 | 0.42 |
| ▸ | SIGMAR1 | Q99720 | 4/20 | 0.41 |
| ▸ | ACHE | P22303 | 1/20 | 0.40 |
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | NR2F2 | P24468 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | EPHX2 | P34913 | 5/20 | 0.39 |
| ▸ | CNR2 | P34972 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29324509 | 0.90 | TLR8 (0.42) | CHRM2CHRM4CHRM1CHRM3ACKR3 | |
| SCHEMBL29324051 | 0.79 | CHRM2 (0.46) | SMN1; SMN2CHRM2CHRM4CHRM1CHRM3 | |
| SCHEMBL18913243 | 0.77 | ACHE (0.54) | CHRM2CHRM4CHRM1CHRM3ACKR3 | |
| SCHEMBL29324512 | 0.77 | DDB1 (0.48) | EPHX2 | |
| SCHEMBL29324505 | 0.76 | CHRM2 (0.43) | CHRM2CHRM4CHRM1CHRM3ACKR3 | |
| SCHEMBL25604354 | 0.73 | SMN1; SMN2 (0.42) | SMN1; SMN2CHRM2CHRM4CHRM1CHRM3 | |
| SCHEMBL23915630 | 0.72 | MAPT (0.54) | SMN1; SMN2CHRM2CHRM4CHRM1CHRM3 | |
| SCHEMBL7971782 | 0.72 | SIGMAR1 (0.69) | ACKR3SIGMAR1 | |
| SCHEMBL29324248 | 0.71 | SMN1; SMN2 (0.41) | SMN1; SMN2NPC1LMNANR2F2HTT | |
| SCHEMBL25825901 | 0.71 | SMN1; SMN2 (0.44) | SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4400499-A1 | GLUTARIMIDE COMPOUND AND USE THEREOF | Medshine Discovery Inc. (CN) | 2024-07-17 | — | — | EP | disclosed |