SCHEMBL29324505

SCHEMBL29324505

CC(C)(C)OC(=O)N1CCN(CCCc2cccc3c(O)cc(=O)oc23)CC1

nearest known ligand 0.45

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
CHRM2 P08172 1/20 0.43
CHRM4 P08173 1/20 0.43
CHRM1 P11229 1/20 0.43
CHRM3 P20309 1/20 0.43
KDM1A O60341 2/20 0.42
CA12 O43570 1/20 0.41
CA1 P00915 1/20 0.41
CA2 P00918 1/20 0.41
CA4 P22748 1/20 0.41
CA5A P35218 1/20 0.41
CA7 P43166 1/20 0.41
CA5B Q9Y2D0 1/20 0.41
CNR2 P34972 1/20 0.41
SIGMAR1 Q99720 2/20 0.40
EPHX2 P34913 4/20 0.40
ACKR3 P25106 3/20 0.39
DTYMK P23919 2/20 0.39
OPRK1 P41145 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29324503 0.80 CHRM2 (0.42) CHRM2CHRM4CHRM1CHRM3KDM1A
SCHEMBL18913243 0.79 ACHE (0.54) CHRM2CHRM4CHRM1CHRM3SIGMAR1
SCHEMBL29324050 0.79 CHRM2 (0.47) CHRM2CHRM4CHRM1CHRM3KDM1A
SCHEMBL29324845 0.78 MAPK8 (0.45) KDM1ACA12CA1CA2EPHX2
SCHEMBL29324508 0.76 SMN1; SMN2 (0.45) CHRM2CHRM4CHRM1CHRM3CNR2
SCHEMBL29324509 0.73 TLR8 (0.42) CHRM2CHRM4CHRM1CHRM3CNR2
SCHEMBL27980806 0.73 SIGMAR1 (0.54) CHRM2CHRM4CHRM1CHRM3KDM1A
SCHEMBL30812306 0.73 SIGMAR1 (0.54) CHRM2CHRM4CHRM1CHRM3KDM1A
SCHEMBL29046356 0.73 MAOB (0.57) EPHX2
SCHEMBL29324722 0.73 GPR119 (0.39) KDM1A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4400499-A1 GLUTARIMIDE COMPOUND AND USE THEREOF Medshine Discovery Inc. (CN) 2024-07-17 EP disclosed