Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.39 |
| ▸ | MEN1 | O00255 | 4/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.39 |
| ▸ | TSHR | P16473 | 2/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.37 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.37 |
| ▸ | PRMT5 | O14744 | 2/20 | 0.36 |
| ▸ | WDR77 | Q9BQA1 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.36 |
| ▸ | BACE1 | P56817 | 1/20 | 0.35 |
| ▸ | CTSS | P25774 | 1/20 | 0.35 |
| ▸ | GLA | P06280 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | ATM | Q13315 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29320347 | 0.85 | ALDH1A1 (0.38) | ALDH1A1MEN1KMT2ATSHRMAPT | |
| SCHEMBL31056568 | 0.82 | PDE4B (0.42) | ALDH1A1MEN1KMT2ANR1H2NR1H3 | |
| SCHEMBL29320350 | 0.78 | ALDH1A1 (0.36) | ALDH1A1MEN1KMT2AMAPTKDM4E | |
| SCHEMBL29324566 | 0.75 | NR1H2 (0.45) | MEN1KMT2ANR1H2NR1H3KDM4E | |
| SCHEMBL31056846 | 0.72 | PDE4B (0.33) | PRMT5WDR77BACE1 | |
| SCHEMBL29320356 | 0.72 | CFB (0.38) | — | |
| SCHEMBL31056597 | 0.72 | CFB (0.38) | — | |
| SCHEMBL29324155 | 0.71 | NR1H2 (0.47) | NR1H2NR1H3 | |
| SCHEMBL29324631 | 0.69 | ALDH1A1 (0.36) | ALDH1A1MEN1KMT2ATSHRMAPT | |
| SCHEMBL31056475 | 0.69 | TMEM97 (0.42) | ALDH1A1MEN1KMT2ATSHRKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024148274-A1 | COMPLEMENT INHIBITION | APELLIS PHARMACEUTICALS, INC. (US) | 2024-07-11 | — | — | WO | disclosed |