Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE4B | Q07343 | 3/20 | 0.33 |
| ▸ | MC4R | P32245 | 1/20 | 0.32 |
| ▸ | MC5R | P33032 | 1/20 | 0.32 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.32 |
| ▸ | PRMT5 | O14744 | 2/20 | 0.32 |
| ▸ | WDR77 | Q9BQA1 | 2/20 | 0.32 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.32 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.32 |
| ▸ | BACE1 | P56817 | 2/20 | 0.31 |
| ▸ | ACACB | O00763 | 1/20 | 0.31 |
| ▸ | ACACA | Q13085 | 1/20 | 0.31 |
| ▸ | ACHE | P22303 | 1/20 | 0.31 |
| ▸ | CCR2 | P41597 | 5/20 | 0.31 |
| ▸ | CCR5 | P51681 | 1/20 | 0.31 |
| ▸ | RORC | P51449 | 1/20 | 0.31 |
| ▸ | CMA1 | P23946 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29320350 | 0.92 | ALDH1A1 (0.36) | PDE4B | |
| SCHEMBL29323913 | 0.80 | RORC (0.33) | MC4RMC5RPRMT5WDR77RORC | |
| SCHEMBL31056475 | 0.79 | TMEM97 (0.42) | PDE4BTMEM97SIGMAR1 | |
| SCHEMBL29323240 | 0.75 | CA12 (0.39) | TMEM97SIGMAR1 | |
| SCHEMBL29320347 | 0.75 | ALDH1A1 (0.38) | PDE4BBACE1ACHE | |
| SCHEMBL29320165 | 0.74 | XIAP (0.34) | TMEM97SIGMAR1CCR2CCR5 | |
| SCHEMBL29324631 | 0.74 | ALDH1A1 (0.36) | PRMT5WDR77TMEM97SIGMAR1CCR5 | |
| SCHEMBL30109296 | 0.73 | HTR7 (0.35) | MC4RMC5RCCR5 | |
| SCHEMBL31269556 | 0.71 | XIAP (0.41) | — | |
| SCHEMBL30109126 | 0.71 | XIAP (0.41) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024148274-A1 | COMPLEMENT INHIBITION | APELLIS PHARMACEUTICALS, INC. (US) | 2024-07-11 | — | — | WO | disclosed |