Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE2A | O00408 | 1/20 | 0.34 |
| ▸ | NR1H4 | Q96RI1 | 4/20 | 0.33 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.33 |
| ▸ | ESRRA | P11474 | 2/20 | 0.32 |
| ▸ | HTR2A | P28223 | 1/20 | 0.32 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.32 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.32 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.31 |
| ▸ | PPARA | Q07869 | 2/20 | 0.31 |
| ▸ | PPARD | Q03181 | 1/20 | 0.31 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.31 |
| ▸ | GPR3 | P46089 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.30 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15496972 | 0.89 | GPR3 (0.42) | NR1H4MRGPRX4KCNH2TRPV1CYP3A4 | |
| SCHEMBL25587215 | 0.79 | PDE2A (0.36) | PDE2AGPR3ALDH1A1MAPT | |
| SCHEMBL25587226 | 0.79 | AR (0.35) | ESRRAGPR3ALDH1A1MAPT | |
| SCHEMBL8225342 | 0.79 | CA1 (0.45) | HTR2ASLC6A4KCNH2TSHRHSP90AA1 | |
| SCHEMBL1980396 | 0.76 | ALDH1A1 (0.43) | MRGPRX4ALDH1A1HSD11B1 | |
| SCHEMBL20763363 | 0.76 | MCL1 (0.45) | MRGPRX4HTR2ASLC6A4KCNH2CYP3A4 | |
| SCHEMBL22904715 | 0.75 | PPARA (0.45) | ESRRAHTR2ASLC6A4KCNH2PPARA | |
| SCHEMBL13141644 | 0.74 | GPR3 (0.42) | NR1H4KCNH2TRPV1CYP3A4MAPK1 | |
| SCHEMBL12733338 | 0.74 | AR (0.44) | NR1H4ESRRAHTR2ASLC6A4KCNH2 | |
| SCHEMBL13762179 | 0.74 | NQO1 (0.46) | CYP3A4TSHRTDP1ALDH1A1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240228484-A1 | MONOACYLGLYCEROL LIPASE MODULATORS | JANSSEN PHARMACEUTICA NV (BE) | 2024-07-11 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240228484-A1 | MONOACYLGLYCEROL LIPASE MODULATORS | MGLL, LPL, PNLIP | PDE2A 724/4885NR1H4 1049/4885MRGPRX4 826/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.