Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NLRP3 | Q96P20 | 6/20 | 0.42 |
| ▸ | IL1B | P01584 | 6/20 | 0.41 |
| ▸ | IDH1 | O75874 | 2/20 | 0.39 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.38 |
| ▸ | TNF | P01375 | 1/20 | 0.38 |
| ▸ | IDH2 | P48735 | 1/20 | 0.38 |
| ▸ | SYK | P43405 | 2/20 | 0.37 |
| ▸ | GPR119 | Q8TDV5 | 2/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | TACR1 | P25103 | 1/20 | 0.36 |
| ▸ | JAK2 | O60674 | 1/20 | 0.36 |
| ▸ | JAK3 | P52333 | 1/20 | 0.36 |
| ▸ | PTK2 | Q05397 | 1/20 | 0.36 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29326283 | 0.92 | NLRP3 (0.42) | NLRP3IL1BIDH1KCNH2TNF | |
| SCHEMBL29326121 | 0.85 | IL1B (0.47) | NLRP3IL1BIDH1IDH2SYK | |
| SCHEMBL29974698 | 0.84 | IL1B (0.52) | NLRP3IL1BIDH1KCNH2MAPT | |
| SCHEMBL29326150 | 0.84 | IL1B (0.52) | NLRP3IL1BIDH1KCNH2MAPT | |
| SCHEMBL29326149 | 0.84 | IL1B (0.52) | NLRP3IL1BIDH1KCNH2MAPT | |
| SCHEMBL29326123 | 0.83 | NLRP3 (0.46) | NLRP3IL1BIDH1KCNH2SYK | |
| SCHEMBL30684770 | 0.82 | NLRP3 (0.44) | NLRP3IL1BKCNH2TNFSYK | |
| SCHEMBL29326130 | 0.82 | NLRP3 (0.44) | NLRP3IL1BKCNH2TNFSYK | |
| SCHEMBL27182184 | 0.79 | IL1B (0.49) | NLRP3IL1BKCNH2JAK2JAK3 | |
| SCHEMBL29326245 | 0.78 | IDH1 (0.38) | IDH1IDH2MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240239758-A1 | SUBSTITUTED TRIAZINE COMPOUND | NICO THERAPEUTICS, INC. | 2024-07-18 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240239758-A1 | SUBSTITUTED TRIAZINE COMPOUND | NLRP3, NLRP1, PYCARD | NLRP3 1/4885IL1B 11/4885IDH1 2485/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.