Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IL1B | P01584 | 6/20 | 0.41 |
| ▸ | NLRP3 | Q96P20 | 6/20 | 0.41 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.36 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.35 |
| ▸ | HCRTR1 | O43613 | 3/20 | 0.34 |
| ▸ | HCRTR2 | O43614 | 2/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.34 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.34 |
| ▸ | TNF | P01375 | 1/20 | 0.34 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.34 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.34 |
| ▸ | SYK | P43405 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29326138 | 0.88 | TRPV1 (0.44) | IL1BNLRP3TRPV1HCRTR1HCRTR2 | |
| SCHEMBL29326156 | 0.81 | NLRP3 (0.41) | IL1BNLRP3KCNH2TNF | |
| SCHEMBL29326134 | 0.80 | TRPV1 (0.43) | TRPV1HCRTR1HCRTR2 | |
| SCHEMBL29326142 | 0.79 | IL1B (0.44) | IL1BNLRP3 | |
| SCHEMBL29326054 | 0.78 | IL1B (0.39) | IL1BP2RX7TNFTSHR | |
| SCHEMBL29326164 | 0.78 | NLRP3 (0.44) | IL1BNLRP3KCNH2TNFSYK | |
| SCHEMBL29326159 | 0.78 | NLRP3 (0.44) | IL1BNLRP3KCNH2TNFSYK | |
| SCHEMBL27182181 | 0.77 | NLRP3 (0.45) | IL1BNLRP3HCRTR1HCRTR2KCNH2 | |
| SCHEMBL29326121 | 0.76 | IL1B (0.47) | IL1BNLRP3TRPV1SYK | |
| SCHEMBL29326825 | 0.75 | BCDIN3D (0.47) | IL1BNLRP3KCNH2TNF |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240239758-A1 | SUBSTITUTED TRIAZINE COMPOUND | NICO THERAPEUTICS, INC. | 2024-07-18 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240239758-A1 | SUBSTITUTED TRIAZINE COMPOUND | NLRP3, NLRP1, PYCARD | IL1B 11/4885NLRP3 1/4885TRPV1 68/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.