Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | JUN | P05412 | 1/20 | 0.43 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.43 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.43 |
| ▸ | RELA | Q04206 | 1/20 | 0.43 |
| ▸ | P2RX1 | P51575 | 1/20 | 0.42 |
| ▸ | TMPRSS4 | Q9NRS4 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 3/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | HPGD | P15428 | 2/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | KDR | P35968 | 1/20 | 0.40 |
| ▸ | SCN10A | Q9Y5Y9 | 2/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | SCN2A | Q99250 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | F12 | P00748 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21756729 | 0.90 | NFKB1 (0.44) | KMT2AJUNNFKB1NFKB2RELA | |
| SCHEMBL29328541 | 0.79 | MEN1 (0.58) | KMT2ANFKB1NFKB2RELAMAPT | |
| SCHEMBL10782143 | 0.78 | MAPT (0.54) | MAPTKDM4EALDH1A1L3MBTL1SMN1; SMN2 | |
| SCHEMBL10778875 | 0.78 | KDM4E (0.49) | KMT2AP2RX1MAPTKDM4EALDH1A1 | |
| SCHEMBL30801100 | 0.71 | MAPT (0.48) | KMT2AP2RX1TMPRSS4MAPTKDM4E | |
| SCHEMBL19989306 | 0.71 | MAPT (0.48) | KMT2AP2RX1TMPRSS4MAPTKDM4E | |
| SCHEMBL9147008 | 0.71 | GAA (0.51) | KMT2AKDM4EALDH1A1L3MBTL1SMN1; SMN2 | |
| SCHEMBL2381677 | 0.70 | MEN1 (0.59) | KMT2AP2RX1TMPRSS4MAPTKDM4E | |
| SCHEMBL25999798 | 0.70 | MEN1 (0.61) | KMT2AMAPTALDH1A1SMN1; SMN2TP53 | |
| SCHEMBL10778855 | 0.70 | CYP1A2 (0.53) | KMT2AALDH1A1HPGDL3MBTL1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12043601-B2 | N-substituted-1H-1,2,4-triazole-3-carboxamides, analogues thereof, and methods of treatment using same | THE REGENTS OF THE UNIVERSITY OF COLORADO (US) | 2024-07-23 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-12043601-B2 | N-substituted-1H-1,2,4-triazole-3-carboxamides, analogues thereof, and methods of treatment using same | BAK1, NAAA, CASP3 | KMT2A 299/4885JUN 1449/4885NFKB1 1291/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.