Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 8/20 | 0.58 |
| ▸ | KMT2A | Q03164 | 8/20 | 0.58 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.58 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.58 |
| ▸ | MAPT | P10636 | 1/20 | 0.58 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.55 |
| ▸ | LMNA | P02545 | 2/20 | 0.53 |
| ▸ | FLT3 | P36888 | 1/20 | 0.52 |
| ▸ | MAP4K1 | Q92918 | 1/20 | 0.52 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.51 |
| ▸ | KCNK3 | O14649 | 3/20 | 0.51 |
| ▸ | KCNK9 | Q9NPC2 | 3/20 | 0.51 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.51 |
| ▸ | NPC1 | O15118 | 4/20 | 0.51 |
| ▸ | RAB9A | P51151 | 4/20 | 0.51 |
| ▸ | TP53 | P04637 | 2/20 | 0.51 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.51 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.51 |
| ▸ | RELA | Q04206 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10782143 | 0.82 | MAPT (0.54) | SMN1; SMN2ALDH1A1KDM4EMAPTFLT3 | |
| SCHEMBL9147008 | 0.82 | GAA (0.51) | KMT2ASMN1; SMN2ALDH1A1KDM4EFLT3 | |
| SCHEMBL29328539 | 0.79 | KMT2A (0.43) | MEN1KMT2ASMN1; SMN2ALDH1A1KDM4E | |
| SCHEMBL31013607 | 0.78 | ALDH1A1 (0.55) | ALDH1A1MAPTNPC1RAB9ATSHR | |
| SCHEMBL21756728 | 0.78 | ALDH1A1 (0.55) | ALDH1A1MAPTNPC1RAB9ATSHR | |
| SCHEMBL29328528 | 0.77 | MMP13 (0.60) | ALDH1A1KDM4EHSD17B10POLB | |
| SCHEMBL21752130 | 0.76 | SMN1; SMN2 (0.58) | MEN1KMT2ASMN1; SMN2ALDH1A1KDM4E | |
| SCHEMBL18965783 | 0.76 | FLT3 (0.54) | MEN1KMT2ASMN1; SMN2ALDH1A1KDM4E | |
| SCHEMBL30677473 | 0.75 | MEN1 (0.58) | MEN1KMT2ASMN1; SMN2ALDH1A1KDM4E | |
| SCHEMBL259299 | 0.75 | FLT3 (0.53) | MEN1KMT2ASMN1; SMN2ALDH1A1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12043601-B2 | N-substituted-1H-1,2,4-triazole-3-carboxamides, analogues thereof, and methods of treatment using same | THE REGENTS OF THE UNIVERSITY OF COLORADO (US) | 2024-07-23 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-12043601-B2 | N-substituted-1H-1,2,4-triazole-3-carboxamides, analogues thereof, and methods of treatment using same | BAK1, NAAA, CASP3 | MEN1 3439/4885KMT2A 299/4885SMN1; SMN2 2714/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.