Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPC5 | Q9UL62 | 2/20 | 0.34 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.33 |
| ▸ | RBP4 | P02753 | 4/20 | 0.33 |
| ▸ | DPP4 | P27487 | 10/20 | 0.33 |
| ▸ | DPP8 | Q6V1X1 | 9/20 | 0.33 |
| ▸ | DPP7 | Q9UHL4 | 7/20 | 0.33 |
| ▸ | DPP9 | Q86TI2 | 3/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.31 |
| ▸ | CDK2 | P24941 | 1/20 | 0.31 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29328686 | 0.82 | P2RX7 (0.36) | TRPC5DPP4DPP8DPP7P2RX7 | |
| SCHEMBL29330071 | 0.82 | PTPN11 (0.34) | TRPC5PTPN11RBP4DPP4DPP8 | |
| SCHEMBL29330133 | 0.81 | PTPN11 (0.35) | TRPC5PTPN11RBP4DPP4DPP8 | |
| SCHEMBL29329900 | 0.80 | P2RX7 (0.37) | TRPC5PTPN11RBP4DPP4DPP8 | |
| SCHEMBL29329821 | 0.80 | TRPC5 (0.35) | TRPC5PTPN11RBP4 | |
| SCHEMBL29330501 | 0.77 | MKNK1 (0.36) | DPP4DPP8DPP7P2RX7 | |
| SCHEMBL29330913 | 0.72 | P2RX7 (0.36) | TRPC5RBP4P2RX7 | |
| SCHEMBL29329825 | 0.70 | TRPC5 (0.56) | TRPC5PTPN11 | |
| SCHEMBL29329976 | 0.70 | PARP1 (0.42) | TRPC5PTPN11P2RX7 | |
| SCHEMBL29330191 | 0.69 | MKNK1 (0.43) | PTPN11RBP4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4400500-A1 | HALOGEN-SUBSTITUTED PYRIDAZINONE COMPOUND AND APPLICATION THEREOF | Medshine Discovery Inc. (CN) | 2024-07-17 | — | — | EP | disclosed |