Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHEK2 | O96017 | 2/20 | 0.47 |
| ▸ | GPR119 | Q8TDV5 | 12/20 | 0.44 |
| ▸ | TGFBR1 | P36897 | 1/20 | 0.41 |
| ▸ | CETP | P11597 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29328995 | 0.94 | CHEK2 (0.46) | CHEK2GPR119TGFBR1CETP | |
| SCHEMBL29328999 | 0.93 | JAK3 (0.40) | CHEK2GPR119TGFBR1 | |
| SCHEMBL29329004 | 0.86 | PRKCQ (0.38) | — | |
| SCHEMBL29330247 | 0.83 | NFE2L2 (0.38) | — | |
| SCHEMBL29329943 | 0.76 | SYK (0.37) | — | |
| SCHEMBL29329117 | 0.76 | CDK2 (0.39) | — | |
| SCHEMBL29328882 | 0.75 | SCN9A (0.36) | — | |
| SCHEMBL31752455 | 0.75 | GPR119 (0.56) | CHEK2GPR119 | |
| SCHEMBL29328808 | 0.74 | PRKCQ (0.41) | — | |
| SCHEMBL1714269 | 0.74 | GPR119 (0.64) | CHEK2GPR119 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024151919-A1 | COMPOUNDS AND COMPOSITIONS FOR TREATING CONDITIONS ASSOCIATED WITH STING ACTIVITY | IFM DUE, INC. (US) | 2024-07-18 | — | — | WO | disclosed |