Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRKCQ | Q04759 | 7/20 | 0.38 |
| ▸ | PRKCD | Q05655 | 1/20 | 0.38 |
| ▸ | SYK | P43405 | 6/20 | 0.37 |
| ▸ | ESR1 | P03372 | 2/20 | 0.36 |
| ▸ | RET | P07949 | 1/20 | 0.35 |
| ▸ | EGFR | P00533 | 1/20 | 0.35 |
| ▸ | ABL1 | P00519 | 1/20 | 0.34 |
| ▸ | BCR | P11274 | 1/20 | 0.34 |
| ▸ | CTSS | P25774 | 1/20 | 0.34 |
| ▸ | JAK2 | O60674 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29330247 | 0.95 | NFE2L2 (0.38) | PRKCQPRKCDSYKESR1RET | |
| SCHEMBL29328882 | 0.88 | SCN9A (0.36) | PRKCQPRKCDSYKESR1RET | |
| SCHEMBL29329943 | 0.87 | SYK (0.37) | PRKCQPRKCDSYKESR1RET | |
| SCHEMBL29329117 | 0.87 | CDK2 (0.39) | PRKCQPRKCDSYKESR1 | |
| SCHEMBL29329640 | 0.86 | SLC6A2 (0.39) | PRKCQPRKCDSYKESR1RET | |
| SCHEMBL29328816 | 0.86 | CHEK2 (0.47) | — | |
| SCHEMBL29328808 | 0.85 | PRKCQ (0.41) | PRKCQPRKCDSYKESR1RET | |
| SCHEMBL29329211 | 0.84 | SYK (0.36) | PRKCQPRKCDSYKESR1RET | |
| SCHEMBL29328658 | 0.83 | MET (0.37) | PRKCQPRKCDSYKESR1RET | |
| SCHEMBL29329290 | 0.83 | PRKCQ (0.42) | PRKCQPRKCDSYKESR1RET |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024151919-A1 | COMPOUNDS AND COMPOSITIONS FOR TREATING CONDITIONS ASSOCIATED WITH STING ACTIVITY | IFM DUE, INC. (US) | 2024-07-18 | — | — | WO | disclosed |