Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SYK | P43405 | 3/20 | 0.37 |
| ▸ | PRKCQ | Q04759 | 5/20 | 0.37 |
| ▸ | SLC6A2 | P23975 | 3/20 | 0.36 |
| ▸ | SLC6A4 | P31645 | 3/20 | 0.36 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.36 |
| ▸ | PRKCD | Q05655 | 1/20 | 0.36 |
| ▸ | RET | P07949 | 1/20 | 0.36 |
| ▸ | HTR3A | P46098 | 1/20 | 0.35 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.35 |
| ▸ | ESR1 | P03372 | 2/20 | 0.34 |
| ▸ | P2RX3 | P56373 | 3/20 | 0.34 |
| ▸ | EGFR | P00533 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29329117 | 0.90 | CDK2 (0.39) | SYKPRKCQSLC6A2SLC6A4SLC6A3 | |
| SCHEMBL29329640 | 0.89 | SLC6A2 (0.39) | SYKPRKCQSLC6A2SLC6A4SLC6A3 | |
| SCHEMBL29328882 | 0.89 | SCN9A (0.36) | SYKPRKCQSLC6A2SLC6A4SLC6A3 | |
| SCHEMBL29328808 | 0.89 | PRKCQ (0.41) | SYKPRKCQSLC6A2SLC6A4SLC6A3 | |
| SCHEMBL29329004 | 0.87 | PRKCQ (0.38) | SYKPRKCQPRKCDRETESR1 | |
| SCHEMBL29329211 | 0.87 | SYK (0.36) | SYKPRKCQSLC6A2SLC6A4SLC6A3 | |
| SCHEMBL29329212 | 0.83 | LRRK2 (0.36) | SYKPRKCQSLC6A2SLC6A4SLC6A3 | |
| SCHEMBL29330247 | 0.83 | NFE2L2 (0.38) | SYKPRKCQPRKCDRETESR1 | |
| SCHEMBL29328658 | 0.81 | MET (0.37) | SYKPRKCQPRKCDRETESR1 | |
| SCHEMBL22803670 | 0.78 | ESR1 (0.44) | SYKPRKCQRETESR1EGFR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024151919-A1 | COMPOUNDS AND COMPOSITIONS FOR TREATING CONDITIONS ASSOCIATED WITH STING ACTIVITY | IFM DUE, INC. (US) | 2024-07-18 | — | — | WO | disclosed |