Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CDK2 | P24941 | 6/20 | 0.39 |
| ▸ | CDK1 | P06493 | 5/20 | 0.39 |
| ▸ | CCNB1 | P14635 | 5/20 | 0.39 |
| ▸ | CCNA2 | P20248 | 4/20 | 0.38 |
| ▸ | CCNA1 | P78396 | 4/20 | 0.38 |
| ▸ | CCNB2 | O95067 | 3/20 | 0.38 |
| ▸ | CCNB3 | Q8WWL7 | 3/20 | 0.38 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.38 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.38 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.38 |
| ▸ | SYK | P43405 | 3/20 | 0.37 |
| ▸ | HTR3A | P46098 | 1/20 | 0.36 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.36 |
| ▸ | CCNT1 | O60563 | 1/20 | 0.36 |
| ▸ | CDK7 | P50613 | 1/20 | 0.36 |
| ▸ | CDK9 | P50750 | 1/20 | 0.36 |
| ▸ | CCNH | P51946 | 1/20 | 0.36 |
| ▸ | CDK5 | Q00535 | 1/20 | 0.36 |
| ▸ | PRKCQ | Q04759 | 5/20 | 0.36 |
| ▸ | PARP15 | Q460N3 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29330247 | 0.92 | NFE2L2 (0.38) | CDK2CDK1CCNB1CCNA2CCNA1 | |
| SCHEMBL29328808 | 0.90 | PRKCQ (0.41) | SLC6A2SLC6A4SLC6A3SYKHTR3A | |
| SCHEMBL29329943 | 0.90 | SYK (0.37) | SLC6A2SLC6A4SLC6A3SYKHTR3A | |
| SCHEMBL29329640 | 0.89 | SLC6A2 (0.39) | SLC6A2SLC6A4SLC6A3SYKHTR3A | |
| SCHEMBL29329211 | 0.89 | SYK (0.36) | SLC6A2SLC6A4SLC6A3SYKHTR3A | |
| SCHEMBL29328882 | 0.89 | SCN9A (0.36) | SLC6A2SLC6A4SLC6A3SYKHTR3A | |
| SCHEMBL29329004 | 0.87 | PRKCQ (0.38) | SYKPRKCQESR1PRKCD | |
| SCHEMBL29329002 | 0.87 | SYK (0.38) | CDK1SYKPRKCQESR1 | |
| SCHEMBL29329212 | 0.85 | LRRK2 (0.36) | SLC6A2SLC6A4SLC6A3SYKHTR3A | |
| SCHEMBL29331087 | 0.83 | PRKCQ (0.36) | CDK1SYKPRKCQESR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024151919-A1 | COMPOUNDS AND COMPOSITIONS FOR TREATING CONDITIONS ASSOCIATED WITH STING ACTIVITY | IFM DUE, INC. (US) | 2024-07-18 | — | — | WO | disclosed |