Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRKCQ | Q04759 | 4/20 | 0.37 |
| ▸ | GALR2 | O43603 | 4/20 | 0.37 |
| ▸ | GALR1 | P47211 | 4/20 | 0.37 |
| ▸ | ESR1 | P03372 | 2/20 | 0.36 |
| ▸ | SYK | P43405 | 2/20 | 0.35 |
| ▸ | RXFP2 | Q8WXD0 | 1/20 | 0.35 |
| ▸ | CTSK | P43235 | 2/20 | 0.34 |
| ▸ | CTSL | P07711 | 1/20 | 0.34 |
| ▸ | CTSS | P25774 | 1/20 | 0.34 |
| ▸ | RET | P07949 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | PRKCD | Q05655 | 1/20 | 0.33 |
| ▸ | CDC7 | O00311 | 1/20 | 0.33 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29329002 | 0.85 | SYK (0.38) | PRKCQGALR2GALR1ESR1SYK | |
| SCHEMBL29329117 | 0.82 | CDK2 (0.39) | PRKCQESR1SYKPRKCD | |
| SCHEMBL29331087 | 0.82 | PRKCQ (0.36) | PRKCQESR1SYKRXFP2CTSK | |
| SCHEMBL29329935 | 0.81 | SCN5A (0.39) | PRKCQGALR2GALR1ESR1SYK | |
| SCHEMBL29330247 | 0.81 | NFE2L2 (0.38) | PRKCQESR1SYKCTSSRET | |
| SCHEMBL29329367 | 0.80 | PRKCQ (0.40) | PRKCQESR1SYKRETMAPT | |
| SCHEMBL29330425 | 0.78 | ESR1 (0.42) | PRKCQESR1SYKRETPOLB | |
| SCHEMBL29329004 | 0.77 | PRKCQ (0.38) | PRKCQESR1SYKCTSSRET | |
| SCHEMBL29330567 | 0.77 | PRKCQ (0.45) | PRKCQESR1SYKRETPOLB | |
| SCHEMBL22803670 | 0.75 | ESR1 (0.44) | PRKCQESR1SYKRET |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024151919-A1 | COMPOUNDS AND COMPOSITIONS FOR TREATING CONDITIONS ASSOCIATED WITH STING ACTIVITY | IFM DUE, INC. (US) | 2024-07-18 | — | — | WO | disclosed |