Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A2 | P23975 | 4/20 | 0.39 |
| ▸ | SLC6A4 | P31645 | 4/20 | 0.39 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.39 |
| ▸ | HTR3A | P46098 | 1/20 | 0.38 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.38 |
| ▸ | ESR1 | P03372 | 1/20 | 0.37 |
| ▸ | PRKCQ | Q04759 | 5/20 | 0.37 |
| ▸ | PRKCD | Q05655 | 1/20 | 0.37 |
| ▸ | TTBK1 | Q5TCY1 | 1/20 | 0.36 |
| ▸ | TTBK2 | Q6IQ55 | 1/20 | 0.36 |
| ▸ | SYK | P43405 | 3/20 | 0.36 |
| ▸ | SCN8A | Q9UQD0 | 1/20 | 0.35 |
| ▸ | SCN10A | Q9Y5Y9 | 1/20 | 0.35 |
| ▸ | RET | P07949 | 1/20 | 0.34 |
| ▸ | EGFR | P00533 | 1/20 | 0.34 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.33 |
| ▸ | CSNK1A1 | P48729 | 1/20 | 0.33 |
| ▸ | CSNK1D | P48730 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29329943 | 0.89 | SYK (0.37) | SLC6A2SLC6A4SLC6A3HTR3AKCNH2 | |
| SCHEMBL29328658 | 0.89 | MET (0.37) | ESR1PRKCQPRKCDSYKRET | |
| SCHEMBL29329117 | 0.89 | CDK2 (0.39) | SLC6A2SLC6A4SLC6A3HTR3AKCNH2 | |
| SCHEMBL29330161 | 0.88 | ESR1 (0.48) | KCNH2ESR1PRKCQPRKCDTTBK1 | |
| SCHEMBL29328882 | 0.88 | SCN9A (0.36) | SLC6A2SLC6A4SLC6A3HTR3AKCNH2 | |
| SCHEMBL29328808 | 0.87 | PRKCQ (0.41) | SLC6A2SLC6A4SLC6A3HTR3AKCNH2 | |
| SCHEMBL29329004 | 0.86 | PRKCQ (0.38) | ESR1PRKCQPRKCDSYKRET | |
| SCHEMBL29330567 | 0.86 | PRKCQ (0.45) | ESR1PRKCQPRKCDTTBK1TTBK2 | |
| SCHEMBL29330255 | 0.85 | ESR1 (0.42) | KCNH2ESR1PRKCQTTBK1TTBK2 | |
| SCHEMBL29330425 | 0.85 | ESR1 (0.42) | KCNH2ESR1PRKCQPRKCDTTBK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024151919-A1 | COMPOUNDS AND COMPOSITIONS FOR TREATING CONDITIONS ASSOCIATED WITH STING ACTIVITY | IFM DUE, INC. (US) | 2024-07-18 | — | — | WO | disclosed |