Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.36 |
| ▸ | SYK | P43405 | 3/20 | 0.35 |
| ▸ | PRKCQ | Q04759 | 5/20 | 0.34 |
| ▸ | PRKCD | Q05655 | 1/20 | 0.33 |
| ▸ | SLC6A2 | P23975 | 4/20 | 0.32 |
| ▸ | SLC6A4 | P31645 | 4/20 | 0.32 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.32 |
| ▸ | ESR1 | P03372 | 1/20 | 0.32 |
| ▸ | MET | P08581 | 1/20 | 0.32 |
| ▸ | RET | P07949 | 1/20 | 0.32 |
| ▸ | IDH1 | O75874 | 2/20 | 0.32 |
| ▸ | EGFR | P00533 | 1/20 | 0.32 |
| ▸ | HTR3A | P46098 | 1/20 | 0.31 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29329211 | 0.95 | SYK (0.36) | LRRK2SYKPRKCQPRKCDSLC6A2 | |
| SCHEMBL29329117 | 0.85 | CDK2 (0.39) | SYKPRKCQPRKCDSLC6A2SLC6A4 | |
| SCHEMBL29328882 | 0.84 | SCN9A (0.36) | LRRK2SYKPRKCQPRKCDSLC6A2 | |
| SCHEMBL29329943 | 0.83 | SYK (0.37) | SYKPRKCQPRKCDSLC6A2SLC6A4 | |
| SCHEMBL29328808 | 0.83 | PRKCQ (0.41) | SYKPRKCQPRKCDSLC6A2SLC6A4 | |
| SCHEMBL29329640 | 0.82 | SLC6A2 (0.39) | SYKPRKCQPRKCDSLC6A2SLC6A4 | |
| SCHEMBL29329004 | 0.82 | PRKCQ (0.38) | SYKPRKCQPRKCDESR1RET | |
| SCHEMBL29330247 | 0.80 | NFE2L2 (0.38) | SYKPRKCQPRKCDESR1RET | |
| SCHEMBL29329365 | 0.79 | MET (0.40) | SYKPRKCQPRKCDESR1MET | |
| SCHEMBL29330570 | 0.79 | APP (0.36) | LRRK2METIDH1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024151919-A1 | COMPOUNDS AND COMPOSITIONS FOR TREATING CONDITIONS ASSOCIATED WITH STING ACTIVITY | IFM DUE, INC. (US) | 2024-07-18 | — | — | WO | disclosed |