Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2C | P28335 | 8/20 | 0.37 |
| ▸ | HTR2B | P41595 | 8/20 | 0.37 |
| ▸ | HTR2A | P28223 | 7/20 | 0.37 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.36 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.33 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.33 |
| ▸ | TRPV1 | Q8NER1 | 4/20 | 0.32 |
| ▸ | AURKA | O14965 | 1/20 | 0.32 |
| ▸ | TRPC5 | Q9UL62 | 1/20 | 0.31 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.31 |
| ▸ | IDO1 | P14902 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29330192 | 0.86 | PTPN11 (0.38) | HTR2CHTR2BHTR2APTPN11SLC6A2 | |
| SCHEMBL29330067 | 0.82 | PTPN11 (0.35) | HTR2CHTR2BHTR2APTPN11SLC6A2 | |
| SCHEMBL29329813 | 0.81 | TRPC5 (0.47) | HTR2CHTR2BHTR2ASLC6A2SLC6A4 | |
| SCHEMBL29329164 | 0.77 | PTPN11 (0.38) | HTR2CHTR2BHTR2APTPN11AURKA | |
| SCHEMBL30603347 | 0.77 | PTPN11 (0.38) | HTR2CHTR2BHTR2APTPN11AURKA | |
| SCHEMBL21807302 | 0.68 | TRPC5 (0.48) | HTR2CHTR2BHTR2ASLC6A2SLC6A4 | |
| SCHEMBL4864805 | 0.67 | TRPV1 (0.57) | HTR2CHTR2BHTR2ATRPV1 | |
| SCHEMBL29329546 | 0.67 | MKNK1 (0.35) | IDO1 | |
| SCHEMBL29090285 | 0.66 | DRD2 (0.36) | HTR2C | |
| SCHEMBL30603355 | 0.66 | DRD2 (0.36) | HTR2C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4400500-A1 | HALOGEN-SUBSTITUTED PYRIDAZINONE COMPOUND AND APPLICATION THEREOF | Medshine Discovery Inc. (CN) | 2024-07-17 | — | — | EP | disclosed |