Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRKCQ | Q04759 | 8/20 | 0.39 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.37 |
| ▸ | PRKCD | Q05655 | 2/20 | 0.37 |
| ▸ | CHEK1 | O14757 | 2/20 | 0.35 |
| ▸ | SYK | P43405 | 2/20 | 0.34 |
| ▸ | CDK1 | P06493 | 2/20 | 0.34 |
| ▸ | KDR | P35968 | 2/20 | 0.34 |
| ▸ | ALOX5AP | P20292 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | ESR1 | P03372 | 1/20 | 0.33 |
| ▸ | LYN | P07948 | 1/20 | 0.33 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.33 |
| ▸ | RET | P07949 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29329290 | 0.87 | PRKCQ (0.42) | PRKCQPRKCDSYKCDK1KDR | |
| SCHEMBL29330026 | 0.86 | SIRT2 (0.40) | PRKCQSIRT2PRKCDSYKESR1 | |
| SCHEMBL29328815 | 0.84 | MAOB (0.40) | PRKCQSIRT2PRKCDCHEK1SYK | |
| SCHEMBL29328881 | 0.83 | SYK (0.38) | PRKCQPRKCDSYKCDK1KDR | |
| SCHEMBL29329785 | 0.83 | SYK (0.39) | PRKCQPRKCDSYKESR1RET | |
| SCHEMBL29329365 | 0.82 | MET (0.40) | PRKCQPRKCDSYKCDK1KDR | |
| SCHEMBL29330430 | 0.82 | PRKCQ (0.43) | PRKCQSIRT2SYKMAPT | |
| SCHEMBL29330563 | 0.81 | PRKCQ (0.39) | PRKCQSIRT2PRKCDSYKESR1 | |
| SCHEMBL29329726 | 0.81 | SYK (0.39) | PRKCQPRKCDSYKCDK1KDR | |
| SCHEMBL29329867 | 0.81 | PRKCQ (0.40) | PRKCQSIRT2PRKCDSYKCDK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024151919-A1 | COMPOUNDS AND COMPOSITIONS FOR TREATING CONDITIONS ASSOCIATED WITH STING ACTIVITY | IFM DUE, INC. (US) | 2024-07-18 | — | — | WO | disclosed |