SCHEMBL29329290

SCHEMBL29329290

N#Cc1cc(OCCc2ccccc2)cc(Nc2ccc3cc[nH]c3c2)n1

nearest known ligand 0.42

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
PRKCQ Q04759 9/20 0.42
KDR P35968 3/20 0.38
EGFR P00533 1/20 0.38
PRKCD Q05655 3/20 0.37
SYK P43405 2/20 0.36
MET P08581 1/20 0.36
ABCG2 Q9UNQ0 2/20 0.36
PDGFRB P09619 1/20 0.36
ESR1 P03372 1/20 0.35
NOTUM Q6P988 1/20 0.35
RET P07949 1/20 0.35
LYN P07948 1/20 0.35
CDK1 P06493 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29329365 0.91 MET (0.40) PRKCQKDRPRKCDSYKMET
SCHEMBL29330430 0.91 PRKCQ (0.43) PRKCQEGFRSYK
SCHEMBL29330563 0.91 PRKCQ (0.39) PRKCQEGFRPRKCDSYKMET
SCHEMBL29328815 0.90 MAOB (0.40) PRKCQPRKCDSYKMET
SCHEMBL29329726 0.88 SYK (0.39) PRKCQKDREGFRPRKCDSYK
SCHEMBL29329867 0.88 PRKCQ (0.40) PRKCQKDREGFRPRKCDSYK
SCHEMBL29329368 0.87 ESR1 (0.41) PRKCQMETESR1
SCHEMBL29329725 0.87 PRKCQ (0.40) PRKCQKDREGFRPRKCDSYK
SCHEMBL29330167 0.87 PRKCQ (0.39) PRKCQKDRPRKCDSYKESR1
SCHEMBL29330567 0.84 PRKCQ (0.45) PRKCQPRKCDSYKESR1RET

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2024151919-A1 COMPOUNDS AND COMPOSITIONS FOR TREATING CONDITIONS ASSOCIATED WITH STING ACTIVITY IFM DUE, INC. (US) 2024-07-18 WO disclosed