Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 2/20 | 0.40 |
| ▸ | PRKCQ | Q04759 | 7/20 | 0.38 |
| ▸ | SIRT2 | Q8IXJ6 | 2/20 | 0.38 |
| ▸ | HTR2C | P28335 | 1/20 | 0.36 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.36 |
| ▸ | HTR2B | P41595 | 1/20 | 0.36 |
| ▸ | HTR6 | P50406 | 1/20 | 0.36 |
| ▸ | MET | P08581 | 1/20 | 0.35 |
| ▸ | PRKCD | Q05655 | 1/20 | 0.35 |
| ▸ | BACE1 | P56817 | 1/20 | 0.34 |
| ▸ | SYK | P43405 | 2/20 | 0.34 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.34 |
| ▸ | SIRT3 | Q9NTG7 | 1/20 | 0.34 |
| ▸ | CMA1 | P23946 | 1/20 | 0.33 |
| ▸ | AHR | P35869 | 1/20 | 0.33 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29330563 | 0.90 | PRKCQ (0.39) | PRKCQSIRT2SLC6A4METPRKCD | |
| SCHEMBL29329290 | 0.90 | PRKCQ (0.42) | PRKCQMETPRKCDSYK | |
| SCHEMBL29328881 | 0.88 | SYK (0.38) | MAOBPRKCQMETPRKCDSYK | |
| SCHEMBL29329368 | 0.87 | ESR1 (0.41) | PRKCQSIRT2MET | |
| SCHEMBL29329365 | 0.85 | MET (0.40) | MAOBPRKCQMETPRKCDSYK | |
| SCHEMBL29330167 | 0.84 | PRKCQ (0.39) | PRKCQSIRT2PRKCDSYKCHEK1 | |
| SCHEMBL29329726 | 0.84 | SYK (0.39) | PRKCQMETPRKCDSYKAHR | |
| SCHEMBL29329867 | 0.84 | PRKCQ (0.40) | PRKCQSIRT2PRKCDSYKSIRT1 | |
| SCHEMBL29330430 | 0.83 | PRKCQ (0.43) | MAOBPRKCQSIRT2BACE1SYK | |
| SCHEMBL29329866 | 0.82 | PRKCQ (0.38) | PRKCQMETPRKCDSYK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024151919-A1 | COMPOUNDS AND COMPOSITIONS FOR TREATING CONDITIONS ASSOCIATED WITH STING ACTIVITY | IFM DUE, INC. (US) | 2024-07-18 | — | — | WO | disclosed |