Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRNA7 | P36544 | 1/20 | 0.41 |
| ▸ | CSF1R | P07333 | 2/20 | 0.37 |
| ▸ | KIT | P10721 | 1/20 | 0.37 |
| ▸ | SYK | P43405 | 2/20 | 0.36 |
| ▸ | PRKCQ | Q04759 | 5/20 | 0.35 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.34 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.34 |
| ▸ | SIRT3 | Q9NTG7 | 1/20 | 0.34 |
| ▸ | PRKCD | Q05655 | 1/20 | 0.34 |
| ▸ | ESR1 | P03372 | 2/20 | 0.34 |
| ▸ | ABL1 | P00519 | 1/20 | 0.34 |
| ▸ | BCR | P11274 | 1/20 | 0.34 |
| ▸ | APP | P05067 | 2/20 | 0.33 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.33 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.33 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.33 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29330428 | 0.88 | ESR1 (0.42) | CHRNA7SYKPRKCQESR1ABL1 | |
| SCHEMBL29330093 | 0.88 | CHRNA7 (0.41) | CHRNA7SYKPRKCQESR1ABL1 | |
| SCHEMBL29330342 | 0.84 | SYK (0.40) | SYKPRKCQSIRT2SIRT1SIRT3 | |
| SCHEMBL29329869 | 0.84 | ESR1 (0.42) | SIRT2SIRT1SIRT3ESR1 | |
| SCHEMBL29330024 | 0.84 | MAOB (0.37) | SYKPRKCQSIRT2SIRT1SIRT3 | |
| SCHEMBL29330433 | 0.84 | SYK (0.41) | CSF1RSYKPRKCQSIRT2SIRT1 | |
| SCHEMBL29330430 | 0.83 | PRKCQ (0.43) | SYKPRKCQSIRT2SIRT1SIRT3 | |
| SCHEMBL29329528 | 0.83 | SYK (0.36) | SYKPRKCQSIRT2SIRT1SIRT3 | |
| SCHEMBL24539425 | 0.82 | APP (0.43) | CHRNA7SYKPRKCQESR1ABL1 | |
| SCHEMBL29745759 | 0.82 | APP (0.43) | CHRNA7SYKPRKCQESR1ABL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024151919-A1 | COMPOUNDS AND COMPOSITIONS FOR TREATING CONDITIONS ASSOCIATED WITH STING ACTIVITY | IFM DUE, INC. (US) | 2024-07-18 | — | — | WO | disclosed |