Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR1 | P03372 | 3/20 | 0.42 |
| ▸ | CHRNA7 | P36544 | 3/20 | 0.40 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.40 |
| ▸ | MAOB | P27338 | 5/20 | 0.37 |
| ▸ | EGFR | P00533 | 1/20 | 0.37 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.37 |
| ▸ | KDR | P35968 | 1/20 | 0.37 |
| ▸ | SYK | P43405 | 1/20 | 0.36 |
| ▸ | ABL1 | P00519 | 1/20 | 0.35 |
| ▸ | BCR | P11274 | 1/20 | 0.35 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.35 |
| ▸ | GALR2 | O43603 | 1/20 | 0.35 |
| ▸ | PRKCQ | Q04759 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29329869 | 0.90 | ESR1 (0.42) | ESR1MAOB | |
| SCHEMBL29330343 | 0.88 | CHRNA7 (0.41) | ESR1CHRNA7SYKABL1BCR | |
| SCHEMBL29330430 | 0.88 | PRKCQ (0.43) | MAOBEGFRSYKABL1PRKCQ | |
| SCHEMBL29330248 | 0.88 | ESR1 (0.46) | ESR1CHRNA7KCNH2KDRSYK | |
| SCHEMBL29329528 | 0.87 | SYK (0.36) | ESR1SYKGALR2PRKCQ | |
| SCHEMBL29330342 | 0.87 | SYK (0.40) | ESR1EGFRSYKABL1BCR | |
| SCHEMBL29330433 | 0.86 | SYK (0.41) | ESR1MAOBSYKPRKCQ | |
| SCHEMBL29329369 | 0.85 | PRKCQ (0.34) | ESR1KCNH2EGFRSYKPRKCQ | |
| SCHEMBL29330495 | 0.85 | IMPDH2 (0.38) | MAOBEGFRPDGFRBKDR | |
| SCHEMBL29329120 | 0.84 | PRKCQ (0.34) | ESR1KCNH2EGFRSYKPRMT5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024151919-A1 | COMPOUNDS AND COMPOSITIONS FOR TREATING CONDITIONS ASSOCIATED WITH STING ACTIVITY | IFM DUE, INC. (US) | 2024-07-18 | — | — | WO | disclosed |