Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SYK | P43405 | 3/20 | 0.41 |
| ▸ | CACNA1H | O95180 | 2/20 | 0.37 |
| ▸ | CACNA1G | O43497 | 1/20 | 0.37 |
| ▸ | CACNA1I | Q9P0X4 | 1/20 | 0.37 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.37 |
| ▸ | MET | P08581 | 1/20 | 0.36 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.36 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.36 |
| ▸ | SIRT3 | Q9NTG7 | 1/20 | 0.36 |
| ▸ | PRKCQ | Q04759 | 5/20 | 0.35 |
| ▸ | MAOB | P27338 | 2/20 | 0.35 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.35 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.35 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.35 |
| ▸ | MAOA | P21397 | 1/20 | 0.34 |
| ▸ | CNR1 | P21554 | 1/20 | 0.34 |
| ▸ | PRKCD | Q05655 | 1/20 | 0.34 |
| ▸ | CSF1R | P07333 | 1/20 | 0.34 |
| ▸ | ESR1 | P03372 | 1/20 | 0.34 |
| ▸ | RET | P07949 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29330342 | 0.89 | SYK (0.40) | SYKMETSIRT2SIRT1SIRT3 | |
| SCHEMBL29330430 | 0.86 | PRKCQ (0.43) | SYKSIRT2SIRT1SIRT3PRKCQ | |
| SCHEMBL29330428 | 0.86 | ESR1 (0.42) | SYKPRKCQMAOBESR1 | |
| SCHEMBL29329528 | 0.86 | SYK (0.36) | SYKMETSIRT2SIRT1SIRT3 | |
| SCHEMBL29330254 | 0.85 | SYK (0.42) | SYKMETPRKCQMAOBPRKCD | |
| SCHEMBL29329365 | 0.85 | MET (0.40) | SYKMETPRKCQMAOBPRKCD | |
| SCHEMBL29329292 | 0.84 | SIRT2 (0.41) | SYKMETSIRT2SIRT1SIRT3 | |
| SCHEMBL29329369 | 0.84 | PRKCQ (0.34) | SYKSIRT2SIRT1SIRT3PRKCQ | |
| SCHEMBL29328881 | 0.84 | SYK (0.38) | SYKPDPK1METPRKCQMAOB | |
| SCHEMBL29328744 | 0.83 | SYK (0.39) | SYKMETPRKCQPRKCDESR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024151919-A1 | COMPOUNDS AND COMPOSITIONS FOR TREATING CONDITIONS ASSOCIATED WITH STING ACTIVITY | IFM DUE, INC. (US) | 2024-07-18 | — | — | WO | disclosed |