Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SYK | P43405 | 2/20 | 0.36 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.35 |
| ▸ | GALR2 | O43603 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | PRKCQ | Q04759 | 5/20 | 0.34 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.34 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.34 |
| ▸ | SIRT3 | Q9NTG7 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | GALR1 | P47211 | 1/20 | 0.34 |
| ▸ | PRKCD | Q05655 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29329944 | 0.91 | SIRT2 (0.41) | SYKGALR2PRKCQSIRT2SIRT1 | |
| SCHEMBL29330430 | 0.88 | PRKCQ (0.43) | SYKMEN1NPC1TP53RAB9A | |
| SCHEMBL29330428 | 0.87 | ESR1 (0.42) | SYKGALR2PRKCQESR1 | |
| SCHEMBL29330342 | 0.87 | SYK (0.40) | SYKPRKCQSIRT2SIRT1SIRT3 | |
| SCHEMBL29330433 | 0.86 | SYK (0.41) | SYKPRKCQSIRT2SIRT1SIRT3 | |
| SCHEMBL29329369 | 0.85 | PRKCQ (0.34) | SYKPRKCQSIRT2SIRT1SIRT3 | |
| SCHEMBL29329120 | 0.84 | PRKCQ (0.34) | SYKPRKCQSIRT2SIRT1SIRT3 | |
| SCHEMBL29330343 | 0.83 | CHRNA7 (0.41) | SYKPRKCQSIRT2SIRT1SIRT3 | |
| SCHEMBL29329365 | 0.82 | MET (0.40) | SYKPRKCQPRKCDESR1MET | |
| SCHEMBL29329292 | 0.81 | SIRT2 (0.41) | SYKNPC1TP53RAB9APRKCQ |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024151919-A1 | COMPOUNDS AND COMPOSITIONS FOR TREATING CONDITIONS ASSOCIATED WITH STING ACTIVITY | IFM DUE, INC. (US) | 2024-07-18 | — | — | WO | disclosed |