Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.55 |
| ▸ | HTT | P42858 | 2/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.55 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.49 |
| ▸ | MEN1 | O00255 | 3/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.45 |
| ▸ | RAB9A | P51151 | 2/20 | 0.45 |
| ▸ | HPGD | P15428 | 2/20 | 0.45 |
| ▸ | NPC1 | O15118 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | TP53 | P04637 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.45 |
| ▸ | UTS2R | Q9UKP6 | 3/20 | 0.43 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.43 |
| ▸ | YAP1 | P46937 | 1/20 | 0.43 |
| ▸ | TEAD4 | Q15561 | 1/20 | 0.43 |
| ▸ | RNF4 | P78317 | 1/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
| ▸ | CNR1 | P21554 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21798487 | 0.80 | ALOX5 (0.54) | ALDH1A1ALOX5MEN1KMT2ARAB9A | |
| SCHEMBL21798482 | 0.80 | ALOX5 (0.54) | ALDH1A1ALOX5MEN1KMT2ARAB9A | |
| SCHEMBL29330571 | 0.76 | MC4R (0.46) | ALDH1A1HTTALOX5MEN1KMT2A | |
| SCHEMBL22327660 | 0.75 | ALOX5 (0.49) | ALDH1A1HTTALOX5MEN1KMT2A | |
| SCHEMBL29330568 | 0.75 | SLC2A1 (0.46) | ALDH1A1HTTSMN1; SMN2ALOX5UTS2R | |
| SCHEMBL9732732 | 0.73 | ALDH1A1 (0.61) | ALDH1A1HTTSMN1; SMN2ALOX5RAB9A | |
| SCHEMBL25316112 | 0.73 | ALDH1A1 (0.66) | ALDH1A1HTTSMN1; SMN2MEN1KMT2A | |
| SCHEMBL29330579 | 0.73 | ALOX5 (0.50) | ALDH1A1ALOX5MEN1KMT2AAOC3 | |
| SCHEMBL29330577 | 0.72 | ALOX5 (0.49) | ALDH1A1HTTSMN1; SMN2ALOX5MEN1 | |
| SCHEMBL16291506 | 0.72 | SLC2A1 (0.53) | ALDH1A1ALOX5MEN1KMT2ARAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12043602-B2 | Fendiline derivatives | THE BOARD OF REGENTS OF THE UNIVERSITY OF TEXAS SYSTEM (US) | 2024-07-23 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-12043602-B2 | Fendiline derivatives | CYP11B2, CYP3A7, CYP4F2 | ALDH1A1 292/4885HTT 2604/4885SMN1; SMN2 3014/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.