Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5 | P09917 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | RAB9A | P51151 | 3/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.45 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.45 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.44 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 2/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | UTS2R | Q9UKP6 | 2/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.42 |
| ▸ | NOX1 | Q9Y5S8 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29330579 | 0.86 | ALOX5 (0.50) | ALOX5ALDH1A1KMT2AMEN1OPRM1 | |
| SCHEMBL29330561 | 0.78 | ALOX5 (0.44) | ALOX5ALDH1A1KMT2AMEN1SLC2A1 | |
| SCHEMBL29330576 | 0.76 | MAPT (0.56) | ALDH1A1KMT2AMEN1SMN1; SMN2GAA | |
| SCHEMBL13720973 | 0.76 | ALOX5 (0.41) | ALOX5ALDH1A1KMT2ARAB9AMEN1 | |
| SCHEMBL16291506 | 0.75 | SLC2A1 (0.53) | ALOX5ALDH1A1KMT2ARAB9AMEN1 | |
| SCHEMBL29330568 | 0.75 | SLC2A1 (0.46) | ALOX5ALDH1A1SLC2A1AOC3SMN1; SMN2 | |
| SCHEMBL17754960 | 0.75 | RAB9A (0.51) | ALDH1A1KMT2ARAB9AMEN1AOC3 | |
| SCHEMBL16656812 | 0.74 | ALOX5 (0.51) | ALOX5ALDH1A1KMT2ARAB9AMEN1 | |
| SCHEMBL15037436 | 0.74 | ALDH1A1 (0.51) | ALOX5ALDH1A1KMT2ARAB9AMEN1 | |
| SCHEMBL16656762 | 0.74 | ALOX5 (0.51) | ALOX5ALDH1A1KMT2ARAB9AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12043602-B2 | Fendiline derivatives | THE BOARD OF REGENTS OF THE UNIVERSITY OF TEXAS SYSTEM (US) | 2024-07-23 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-12043602-B2 | Fendiline derivatives | CYP11B2, CYP3A7, CYP4F2 | ALOX5 648/4885ALDH1A1 292/4885KMT2A 3225/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.