Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | NPC1 | O15118 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | GSK3B | P49841 | 1/20 | 0.40 |
| ▸ | GCGR | P47871 | 3/20 | 0.39 |
| ▸ | MAPK14 | Q16539 | 3/20 | 0.39 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.38 |
| ▸ | ERCC1 | P07992 | 1/20 | 0.37 |
| ▸ | ERCC4 | Q92889 | 1/20 | 0.37 |
| ▸ | CTSV | O60911 | 1/20 | 0.37 |
| ▸ | CTSL | P07711 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.36 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.36 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29331889 | 0.81 | MEN1 (0.43) | MEN1NPC1KMT2AGSK3BGCGR | |
| SCHEMBL23920029 | 0.81 | PIM1 (0.47) | MEN1NPC1KMT2AGCGRMAPK14 | |
| SCHEMBL29332771 | 0.68 | GSK3B (0.55) | MEN1NPC1KMT2AGSK3BMAPT | |
| SCHEMBL10993289 | 0.68 | ALDH1A1 (0.65) | MEN1NPC1KMT2AALOX5MAPT | |
| SCHEMBL28779247 | 0.67 | ALDH1A1 (0.58) | MEN1NPC1KMT2AALOX5MAPT | |
| SCHEMBL10357523 | 0.66 | MEN1 (0.78) | MEN1NPC1KMT2AMAPK1MAPT | |
| SCHEMBL31695313 | 0.66 | IL4 (0.54) | MEN1KMT2AGSK3BGCGRMAPK14 | |
| SCHEMBL23841138 | 0.66 | ATM (0.57) | MEN1KMT2AGCGRMAPK14MAPT | |
| SCHEMBL16055422 | 0.66 | TRPA1 (0.45) | MEN1NPC1KMT2AGSK3BMAPK14 | |
| Fluorobenzene SCHEMBL28353608 | 0.64 | ALDH1A1 (0.64) | MEN1NPC1KMT2AALOX5MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12043621-B2 | Small molecule inhibitors of Interleukin-4 | TRUSTEES OF BOSTON UNIVERSITY (US) | 2024-07-23 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-12043621-B2 | Small molecule inhibitors of Interleukin-4 | IL4, IL2, IL4I1 | MEN1 3952/4885NPC1 4117/4885KMT2A 2798/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.