Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | RXRA | P19793 | 3/20 | 0.34 |
| ▸ | GRIN1 | Q05586 | 3/20 | 0.34 |
| ▸ | GRIN2B | Q13224 | 3/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | PDE4A | P27815 | 4/20 | 0.31 |
| ▸ | PTGER1 | P34995 | 2/20 | 0.31 |
| ▸ | PDE4B | Q07343 | 2/20 | 0.31 |
| ▸ | PDE4C | Q08493 | 2/20 | 0.31 |
| ▸ | PDE4D | Q08499 | 2/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | CA2 | P00918 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2067188 | 0.83 | NPC1 (0.37) | NPC1RAB9AMAPTKMT2AALDH1A1 | |
| SCHEMBL31691297 | 0.79 | ALDH1A1 (0.35) | L3MBTL1ALDH1A1CA2 | |
| SCHEMBL5734033 | 0.77 | AGBL2 (0.37) | LMNAPOLBKMT2AALDH1A1CA2 | |
| SCHEMBL2067833 | 0.76 | NOTUM (0.37) | L3MBTL1POLBKMT2AALDH1A1CA2 | |
| SCHEMBL30994666 | 0.75 | SSTR4 (0.39) | KMT2AALDH1A1CA2 | |
| SCHEMBL29333332 | 0.75 | SSTR4 (0.39) | KMT2AALDH1A1CA2 | |
| SCHEMBL27028670 | 0.72 | L3MBTL1 (0.44) | L3MBTL1LMNAPOLBMAPTKMT2A | |
| SCHEMBL29829389 | 0.72 | L3MBTL1 (0.44) | L3MBTL1LMNAPOLBMAPTKMT2A | |
| SCHEMBL21591039 | 0.71 | L3MBTL1 (0.38) | L3MBTL1RXRAGRIN1GRIN2BNPC1 | |
| SCHEMBL21591101 | 0.70 | L3MBTL1 (0.38) | L3MBTL1NPC1RAB9ALMNAPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4648851-A1 | SUBSTITUTED (HETERO)ANILINES AND THEIR USE | Astrazeneca AB (SE) | 2025-11-19 | — | — | EP | disclosed |
| WO-2024149728-A1 | SUBSTITUTED (HETERO)ANILINES AND THEIR USE | ASTRAZENECA AB (SE) | 2024-07-18 | — | — | WO | disclosed |
| WO-2024149728-A1 | SUBSTITUTED (HETERO)ANILINES AND THEIR USE | ASTRAZENECA AB (SE) | 2024-07-18 | — | — | WO | disclosed |