Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SSTR4 | P31391 | 1/20 | 0.39 |
| ▸ | NOTUM | Q6P988 | 3/20 | 0.39 |
| ▸ | POLQ | O75417 | 1/20 | 0.36 |
| ▸ | AGBL2 | Q5U5Z8 | 1/20 | 0.35 |
| ▸ | RET | P07949 | 1/20 | 0.34 |
| ▸ | PRKX | P51817 | 1/20 | 0.34 |
| ▸ | TAOK1 | Q7L7X3 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | GLA | P06280 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.32 |
| ▸ | AR | P10275 | 1/20 | 0.32 |
| ▸ | MAOA | P21397 | 1/20 | 0.32 |
| ▸ | MAOB | P27338 | 1/20 | 0.32 |
| ▸ | ASPH | Q12797 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30994666 | 1.00 | SSTR4 (0.39) | SSTR4NOTUMPOLQAGBL2RET | |
| SCHEMBL31691297 | 0.81 | ALDH1A1 (0.35) | AGBL2ALDH1A1CA2 | |
| SCHEMBL5734033 | 0.79 | AGBL2 (0.37) | AGBL2MEN1KMT2AKDM4ENPSR1 | |
| SCHEMBL2067833 | 0.78 | NOTUM (0.37) | NOTUMMEN1KMT2AKDM4EALDH1A1 | |
| SCHEMBL29728392 | 0.77 | SSTR4 (0.34) | SSTR4POLQAGBL2S1PR4 | |
| SCHEMBL24534080 | 0.77 | SSTR4 (0.35) | SSTR4KMT2AS1PR4 | |
| SCHEMBL2067188 | 0.77 | NPC1 (0.37) | MEN1KMT2ANPSR1ALDH1A1CYP1A2 | |
| SCHEMBL29333320 | 0.75 | L3MBTL1 (0.41) | KMT2AALDH1A1CA2 | |
| SCHEMBL1577283 | 0.75 | CYP11B1 (0.35) | SSTR4NOTUMPOLQAGBL2MEN1 | |
| SCHEMBL3953710 | 0.72 | SSTR4 (0.33) | SSTR4NOTUMPOLQAGBL2MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4648851-A1 | SUBSTITUTED (HETERO)ANILINES AND THEIR USE | Astrazeneca AB (SE) | 2025-11-19 | — | — | EP | disclosed |
| WO-2024149728-A1 | SUBSTITUTED (HETERO)ANILINES AND THEIR USE | ASTRAZENECA AB (SE) | 2024-07-18 | — | — | WO | disclosed |
| WO-2024149728-A1 | SUBSTITUTED (HETERO)ANILINES AND THEIR USE | ASTRAZENECA AB (SE) | 2024-07-18 | — | — | WO | disclosed |