Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 2/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | CES2 | O00748 | 3/20 | 0.45 |
| ▸ | CES1 | P23141 | 3/20 | 0.45 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | MGLL | Q99685 | 1/20 | 0.43 |
| ▸ | FLT1 | P17948 | 1/20 | 0.41 |
| ▸ | FLT4 | P35916 | 1/20 | 0.41 |
| ▸ | KDR | P35968 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | RECQL | P46063 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10389925 | 0.84 | HSD11B1 (0.46) | RAB9AHPGDSMN1; SMN2CES2CES1 | |
| SCHEMBL9493916 | 0.82 | CES2 (0.56) | HPGDCES2CES1ALDH1A1MGLL | |
| SCHEMBL28575134 | 0.80 | MGLL (0.44) | RAB9AHPGDSMN1; SMN2CES2CES1 | |
| SCHEMBL8885921 | 0.80 | CES2 (0.44) | RAB9AHPGDCES2CES1ALDH1A1 | |
| SCHEMBL6807438 | 0.79 | TSHR (0.50) | RAB9AHPGDSMN1; SMN2ALDH1A1FLT1 | |
| SCHEMBL28603923 | 0.79 | NR4A1 (0.68) | RAB9ACES2CES1NR4A1ALDH1A1 | |
| SCHEMBL3695975 | 0.78 | CES2 (0.60) | CES2CES1NR4A1HTTKMT2A | |
| SCHEMBL4286614 | 0.77 | CES2 (0.55) | RAB9AHPGDSMN1; SMN2CES2CES1 | |
| SCHEMBL18892397 | 0.77 | NR4A1 (0.43) | RAB9ASMN1; SMN2CES2CES1NR4A1 | |
| SCHEMBL3138767 | 0.77 | CES2 (0.54) | RAB9AHPGDSMN1; SMN2CES2CES1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2230312-A1 | Probe compound for detecting and isolating enzymes and means and methods using the same | Helmholtz-Zentrum für Infektionsforschung GmbH (DE) | 2010-09-22 | — | — | EP | disclosed |
| CN-1319578-A | Use of 1,1-di (4-chlorophenyl)-2,2,2-trichloroalcohol adduct | ATOCHEM ELF SA (FR) | 2001-10-31 | — | — | CN | disclosed |
| CN-1319579-A | Use of 1,1-di(4-chlorophenyl-2,2,2-trichloroalcohol adduct | ATOCHEM ELF SA (FR) | 2001-10-31 | — | — | CN | disclosed |
| CN-1066701-C | Process for preparing 1, 1-bis (4-chlorophenyl) -2,2, 2-trichloroethanol adducts | ATOCHEM (FR) | 2001-06-06 | — | — | CN | disclosed |
| CN-1039989-C | Process for preparing 1, 1-bis (4-chlorophenyl) -2, 2, 2-trichloroethanol | ATOCHEM (FR) | 1998-09-30 | — | — | CN | disclosed |
| CN-1117957-A | Process for preparing 1, 1-bis (4-chlorophenyl) -2, 2, 2-trichloroethanol adducts | ATOCHEM (FR) | 1996-03-06 | — | — | CN | disclosed |
| CN-1050014-A | Process for preparing 1, 1-bis (4-chlorophenyl) -2, 2, 2-trichloroethanol | ATOCHEM (FR) | 1991-03-20 | — | — | CN | disclosed |
| CN-1050014-A | Process for preparing 1, 1-bis (4-chlorophenyl) -2, 2, 2-trichloroethanol | ATOCHEM (FR) | 1991-03-20 | — | — | CN | disclosed |