SCHEMBL29334085

SCHEMBL29334085

CC(C)(C)OC(=O)N1CCOC=C1c1cc(Cl)cc(-c2ncn(C3CCCCO3)n2)c1

nearest known ligand 0.33

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
USP30 Q70CQ3 2/20 0.33
UCHL1 P09936 2/20 0.33
GPR119 Q8TDV5 1/20 0.32
XPO1 O14980 1/20 0.32
HTR2C P28335 1/20 0.31
SLC6A4 P31645 1/20 0.31
MEN1 O00255 1/20 0.31
KMT2A Q03164 1/20 0.31
ALDH1A1 P00352 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31224635 0.71 HSP90AA1 (0.36) USP30UCHL1MEN1KMT2A
SCHEMBL30855045 0.70 GPR119 (0.38) USP30GPR119MEN1KMT2A
SCHEMBL29334347 0.70 GPR119 (0.38) USP30GPR119MEN1KMT2A
SCHEMBL29334170 0.70 GPR119 (0.35) USP30UCHL1GPR119MEN1KMT2A
SCHEMBL30855145 0.70 GPR119 (0.35) USP30UCHL1GPR119MEN1KMT2A
SCHEMBL29334081 0.69 STS (0.33) USP30UCHL1MEN1KMT2A
SCHEMBL29334072 0.68 USP30 (0.38) USP30MEN1KMT2A
SCHEMBL29334339 0.68 GPR119 (0.38) GPR119
SCHEMBL584032 0.66 YTHDC1 (0.37)
SCHEMBL14839503 0.65 USP30 (0.43) USP30GPR119MEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4594308-A1 N-ACRYLOYLMORPHOLINE DERIVATIVES AS KEAP1 MODULATORS AND USES THEREOF Vividion Therapeutics, Inc. (US) 2025-08-06 EP disclosed
US-20240226114-A1 INHIBITORS AND USES THEREOF VIVIDION THERAPEUTICS, INC. 2024-07-11 US disclosed
US-20240226114-A1 INHIBITORS AND USES THEREOF VIVIDION THERAPEUTICS, INC. 2024-07-11 US disclosed
WO-2024073587-A1 N-ACRYLOYLMORPHOLINE DERIVATIVES AS KEAP1 MODULATORS AND USES THEREOF VIVIDION THERAPEUTICS, INC. (US) 2024-04-04 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20240226114-A1 INHIBITORS AND USES THEREOF KEAP1, NQO1, NFE2L2 USP30 874/4885UCHL1 2968/4885GPR119 2964/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.