Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRM1 | P35372 | 4/20 | 0.52 |
| ▸ | ADAMTS5 | Q9UNA0 | 1/20 | 0.51 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.47 |
| ▸ | BLM | P54132 | 1/20 | 0.43 |
| ▸ | GRM5 | P41594 | 1/20 | 0.43 |
| ▸ | OPRD1 | P41143 | 3/20 | 0.42 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.42 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.42 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | CASP1 | P29466 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | CASP7 | P55210 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18793811 | 0.86 | OPRM1 (0.66) | OPRM1ADAMTS5BLMGRM5OPRD1 | |
| SCHEMBL27099821 | 0.84 | ADAMTS5 (0.51) | OPRM1ADAMTS5BLMGRM5OPRD1 | |
| SCHEMBL27099786 | 0.84 | ADAMTS5 (0.51) | OPRM1ADAMTS5BLMGRM5OPRD1 | |
| SCHEMBL18793808 | 0.84 | LMNA (0.49) | OPRM1SIGMAR1BLMALDH1A1EPHX2 | |
| SCHEMBL18088639 | 0.82 | OPRM1 (0.49) | OPRM1ADAMTS5OPRD1MEN1KMT2A | |
| SCHEMBL13997703 | 0.82 | ADAMTS5 (0.49) | OPRM1ADAMTS5BLMGRM5OPRD1 | |
| SCHEMBL5559794 | 0.82 | OPRM1 (0.47) | OPRM1ADAMTS5OPRD1MEN1KMT2A | |
| SCHEMBL18088809 | 0.81 | ADAMTS5 (0.48) | OPRM1ADAMTS5BLMGRM5MEN1 | |
| SCHEMBL27099820 | 0.81 | ADAMTS5 (0.48) | OPRM1ADAMTS5BLMGRM5OPRD1 | |
| SCHEMBL18088638 | 0.80 | USP2 (0.57) | OPRM1ADAMTS5OPRD1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3365334-B1 | BENZOLACTAM COMPOUNDS AS PROTEIN KINASE INHIBITORS | OTSUKA PHARMA CO LTD (JP) | 2024-07-17 | — | — | EP | disclosed |