Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.40 |
| ▸ | UGT8 | Q16880 | 1/20 | 0.34 |
| ▸ | CYP2D6 | P10635 | 8/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 7/20 | 0.34 |
| ▸ | USP2 | O75604 | 6/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.33 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 3/20 | 0.32 |
| ▸ | TSHR | P16473 | 2/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
| ▸ | NAMPT | P43490 | 1/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.31 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26318126 | 0.79 | ALDH1A1 (0.43) | ALDH1A1UGT8CYP3A4USP2L3MBTL1 | |
| SCHEMBL9911426 | 0.76 | ATM (0.50) | ALDH1A1TSHRL3MBTL1KMT2AMEN1 | |
| SCHEMBL21999479 | 0.76 | ATM (0.45) | ALDH1A1TSHRL3MBTL1KMT2AMEN1 | |
| SCHEMBL25481778 | 0.74 | MEN1 (0.49) | ALDH1A1L3MBTL1KMT2AMEN1HPGD | |
| SCHEMBL29341868 | 0.74 | ALDH1A1 (0.52) | ALDH1A1CYP2D6CYP3A4USP2CYP1A2 | |
| SCHEMBL16181037 | 0.73 | ALDH1A1 (0.35) | ALDH1A1CYP2D6CYP3A4USP2L3MBTL1 | |
| SCHEMBL20061876 | 0.73 | PIK3CD (0.48) | ALDH1A1CYP3A4USP2CYP1A2L3MBTL1 | |
| SCHEMBL21813931 | 0.73 | MEN1 (0.41) | ALDH1A1UGT8CYP3A4USP2L3MBTL1 | |
| SCHEMBL7855456 | 0.73 | TDP1 (0.45) | ALDH1A1CYP1A2L3MBTL1KMT2AHSD17B10 | |
| SCHEMBL20413347 | 0.71 | KDM4E (0.51) | ALDH1A1CYP2D6CYP3A4USP2L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240239774-A1 | SOLUBLE ADENYLYL CYCLASE (SAC) INHIBITORS AND USES THEREOF | CORNELL UNIVERSITY (US) | 2024-07-18 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240239774-A1 | SOLUBLE ADENYLYL CYCLASE (SAC) INHIBITORS AND USES THEREOF | UACA, ADCYAP1R1, ADCY1 | ALDH1A1 638/4885UGT8 451/4885CYP2D6 1242/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.