Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.52 |
| ▸ | CYP2D6 | P10635 | 11/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 8/20 | 0.47 |
| ▸ | USP2 | O75604 | 6/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 4/20 | 0.47 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.46 |
| ▸ | CYP2C9 | P11712 | 4/20 | 0.45 |
| ▸ | TSHR | P16473 | 4/20 | 0.45 |
| ▸ | CYP2C19 | P33261 | 4/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.42 |
| ▸ | HPGD | P15428 | 3/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21655189 | 0.81 | OPRM1 (0.41) | ALDH1A1CYP3A4USP2TSHRHSD17B10 | |
| SCHEMBL277929 | 0.80 | ALDH1A1 (0.55) | ALDH1A1CYP2D6CYP3A4USP2CYP1A2 | |
| SCHEMBL13722312 | 0.79 | ALDH1A1 (0.54) | ALDH1A1CYP2D6CYP3A4USP2CYP1A2 | |
| SCHEMBL22681510 | 0.77 | ALDH1A1 (0.33) | ALDH1A1CYP3A4USP2HSD17B10HPGD | |
| SCHEMBL25810288 | 0.77 | ALDH1A1 (0.55) | ALDH1A1CYP2D6CYP3A4USP2CYP1A2 | |
| SCHEMBL14010813 | 0.75 | — | — | |
| SCHEMBL8402970 | 0.75 | ALDH1A1 (0.51) | ALDH1A1CYP2D6CYP3A4USP2CYP1A2 | |
| SCHEMBL25093262 | 0.75 | ALDH1A1 (0.50) | ALDH1A1CYP2D6CYP3A4USP2CYP1A2 | |
| SCHEMBL17571997 | 0.74 | CYP1A2 (0.41) | ALDH1A1CYP2D6CYP3A4USP2CYP1A2 | |
| SCHEMBL29339644 | 0.74 | ALDH1A1 (0.40) | ALDH1A1CYP2D6CYP3A4USP2CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240239774-A1 | SOLUBLE ADENYLYL CYCLASE (SAC) INHIBITORS AND USES THEREOF | CORNELL UNIVERSITY (US) | 2024-07-18 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240239774-A1 | SOLUBLE ADENYLYL CYCLASE (SAC) INHIBITORS AND USES THEREOF | UACA, ADCYAP1R1, ADCY1 | ALDH1A1 638/4885CYP2D6 1242/4885CYP3A4 1635/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.