SCHEMBL29344435

SCHEMBL29344435

CNC(=O)C(CCCNC(C)O)NC

nearest known ligand 0.39

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
KISS1R Q969F8 1/20 0.39
MMP2 P08253 2/20 0.33
MMP9 P14780 2/20 0.33
MMP8 P22894 2/20 0.33
CACNA1B Q00975 2/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL22293929 0.80 SIRT6 (0.46) KISS1RMMP2MMP9MMP8
SCHEMBL15258555 0.78 FOLH1 (0.34) MMP2MMP9MMP8CACNA1B
SCHEMBL24531193 0.76 C3AR1 (0.38) KISS1RMMP2MMP9CACNA1B
SCHEMBL19057918 0.76 KDM4E (0.48) KISS1RMMP9CACNA1B
SCHEMBL13416823 0.76 KISS1R (0.42) KISS1RMMP2MMP9
SCHEMBL24728478 0.76 MMP2 (0.33) KISS1RMMP2MMP9MMP8CACNA1B
SCHEMBL23893954 0.75 ADH1B (0.41) KISS1RCACNA1B
SCHEMBL20414883 0.75 CA2 (0.44) MMP2MMP9
SCHEMBL13351183 0.75 CA2 (0.44) MMP2MMP9
SCHEMBL21479635 0.75 FOLH1 (0.33)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2024151890-A1 LINKERS, DRUG LINKERS AND CONJUGATES THEREOF AND METHODS OF USING THE SAME PROFOUNDBIO US CO. (US) 2024-07-18 WO disclosed