Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DHFR | P00374 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.35 |
| ▸ | HTT | P42858 | 2/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.35 |
| ▸ | LMNA | P02545 | 2/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.35 |
| ▸ | SLC6A4 | P31645 | 3/20 | 0.35 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.35 |
| ▸ | HTR2A | P28223 | 1/20 | 0.34 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.34 |
| ▸ | PDE9A | O76083 | 2/20 | 0.34 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 3/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29344675 | 0.87 | ALDH1A1 (0.34) | ALDH1A1HTTSMN1; SMN2L3MBTL1KDM4E | |
| SCHEMBL29344733 | 0.83 | ALDH1A1 (0.36) | ALDH1A1HTTSMN1; SMN2LMNAKDM4E | |
| SCHEMBL29344742 | 0.82 | HSP90AA1 (0.33) | KDM4EMEN1KMT2ATSHR | |
| SCHEMBL29344724 | 0.76 | ALDH1A1 (0.31) | ALDH1A1HTTSMN1; SMN2LMNAL3MBTL1 | |
| SCHEMBL29344706 | 0.69 | CDK2 (0.37) | ALDH1A1KDM4EMEN1KMT2A | |
| SCHEMBL23327500 | 0.68 | ALDH1A1 (0.43) | DHFRALDH1A1HTTSMN1; SMN2L3MBTL1 | |
| SCHEMBL26098304 | 0.68 | PTPN1 (0.49) | ALDH1A1HTTSMN1; SMN2L3MBTL1KDM4E | |
| SCHEMBL23351205 | 0.67 | ALDH1A1 (0.35) | ALDH1A1HTTSMN1; SMN2LMNAL3MBTL1 | |
| SCHEMBL23327454 | 0.65 | MAPT (0.42) | ALDH1A1LMNAPOLB | |
| SCHEMBL23327537 | 0.65 | NR3C2 (0.38) | ALDH1A1HTTSMN1; SMN2L3MBTL1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024151992-A1 | PREPARATION OF A TYK2 INHIBITOR | VENTYX BIOSCIENCES, INC. (US) | 2024-07-18 | — | — | WO | disclosed |