Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSP90AA1 | P07900 | 2/20 | 0.33 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.31 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.31 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.30 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.30 |
| ▸ | TSHR | P16473 | 1/20 | 0.30 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29344733 | 0.90 | ALDH1A1 (0.36) | HSP90AA1KDM4EMEN1KMT2A | |
| SCHEMBL29344675 | 0.85 | ALDH1A1 (0.34) | HSP90AA1HSP90AB1KDM4E | |
| SCHEMBL29344718 | 0.82 | DHFR (0.37) | KDM4EMEN1TSHRKMT2A | |
| SCHEMBL29344744 | 0.75 | — | — | |
| SCHEMBL29344706 | 0.71 | CDK2 (0.37) | KDM4EMEN1CYP2C9CYP2C19KMT2A | |
| SCHEMBL23327500 | 0.66 | ALDH1A1 (0.43) | HSP90AA1KDM4EKMT2A | |
| SCHEMBL23351205 | 0.65 | ALDH1A1 (0.35) | HSP90AA1KDM4EMEN1KMT2A | |
| SCHEMBL20689640 | 0.64 | KDM4E (0.46) | KDM4EMEN1TSHRKMT2AHSD17B10 | |
| SCHEMBL20696803 | 0.63 | SMN1; SMN2 (0.43) | KDM4EMEN1TSHRKMT2AHSD17B10 | |
| SCHEMBL21811192 | 0.63 | KDM4E (0.44) | KDM4ETSHRHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024151992-A1 | PREPARATION OF A TYK2 INHIBITOR | VENTYX BIOSCIENCES, INC. (US) | 2024-07-18 | — | — | WO | disclosed |