Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.36 |
| ▸ | LMNA | P02545 | 5/20 | 0.36 |
| ▸ | MAPT | P10636 | 3/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | HPGD | P15428 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | CSF1R | P07333 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 3/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.35 |
| ▸ | GPBAR1 | Q8TDU6 | 1/20 | 0.35 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.34 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | ENPP1 | P22413 | 1/20 | 0.32 |
| ▸ | CACNA1H | O95180 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29344742 | 0.90 | HSP90AA1 (0.33) | KDM4EMEN1KMT2AHSP90AA1 | |
| SCHEMBL29344675 | 0.89 | ALDH1A1 (0.34) | ALDH1A1KDM4ECSF1RPOLBSMN1; SMN2 | |
| SCHEMBL29344718 | 0.83 | DHFR (0.37) | ALDH1A1LMNAKDM4EMEN1KMT2A | |
| SCHEMBL29344736 | 0.76 | CXCR3 (0.32) | ALDH1A1LMNASMN1; SMN2MAPK1GPBAR1 | |
| SCHEMBL29344706 | 0.71 | CDK2 (0.37) | ALDH1A1MAPTKDM4EMEN1HPGD | |
| SCHEMBL23327500 | 0.70 | ALDH1A1 (0.43) | ALDH1A1MAPTKDM4EKMT2AGAA | |
| SCHEMBL23327537 | 0.68 | NR3C2 (0.38) | ALDH1A1KDM4EMEN1KMT2AGAA | |
| SCHEMBL23351205 | 0.68 | ALDH1A1 (0.35) | ALDH1A1LMNAKDM4EMEN1KMT2A | |
| SCHEMBL23327454 | 0.66 | MAPT (0.42) | ALDH1A1LMNAMAPTHPGDPOLB | |
| SCHEMBL21811192 | 0.66 | KDM4E (0.44) | ALDH1A1LMNAMAPTKDM4EHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024151992-A1 | PREPARATION OF A TYK2 INHIBITOR | VENTYX BIOSCIENCES, INC. (US) | 2024-07-18 | — | — | WO | disclosed |