Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAPDH | P04406 | 1/20 | 0.49 |
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | HPGD | P15428 | 2/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.46 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.46 |
| ▸ | CA12 | O43570 | 1/20 | 0.45 |
| ▸ | CA2 | P00918 | 1/20 | 0.45 |
| ▸ | CA9 | Q16790 | 1/20 | 0.45 |
| ▸ | ADORA2A | P29274 | 2/20 | 0.44 |
| ▸ | ADORA1 | P30542 | 2/20 | 0.44 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL2933346 | 0.98 | GAPDH (0.48) | GAPDHMEN1KMT2AKDM4EALDH1A1 | |
| SCHEMBL2937063 | 0.91 | ALOX5 (0.54) | MEN1KMT2AALDH1A1MAPTALOX15 | |
| Hydrochloric Acid SCHEMBL2939395 | 0.89 | ALOX5 (0.53) | MEN1KMT2AKDM4EALDH1A1MAPT | |
| SCHEMBL27947533 | 0.81 | GAPDH (0.49) | GAPDHMEN1KMT2ACA12CA2 | |
| SCHEMBL2939433 | 0.78 | DYRK1A (0.51) | MAPT | |
| SCHEMBL6249208 | 0.77 | CYP3A4 (0.61) | GAPDHMEN1KMT2AKDM4EALDH1A1 | |
| Hydrochloric Acid SCHEMBL2939520 | 0.77 | FABP4 (0.50) | MAPT | |
| SCHEMBL5789891 | 0.76 | ABCG2 (0.52) | MEN1KMT2AKDM4EALDH1A1HPGD | |
| SCHEMBL2938310 | 0.74 | MEN1 (0.50) | MEN1KMT2AKDM4EALDH1A1HPGD | |
| SCHEMBL2937944 | 0.74 | APP (0.54) | MEN1KMT2AKDM4EALDH1A1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1494995-B1 | 3-AMINOPHENOL DERIVATIVES SUBSTITUTED IN THE 2-POSITION, AND DYES CONTAINING THESE COMPOUNDS | PROCTER & GAMBLE (US) | 2010-09-22 | — | — | EP | claimed |
| US-7033401-B2 | 3-Aminophenol derivatives substituted in the 2-position, and dyes containing these compounds | WELLA AG (DE) | 2006-04-25 | — | — | US | claimed |
| CN-1646478-A | 3-aminophenol derivatives substituted in the 2-position and colorants comprising the same | P & G CLAIROL INC (US) | 2005-07-27 | — | — | CN | claimed |
| EP-1494995-A1 | 3-AMINOPHENOL DERIVATIVES SUBSTITUTED IN THE 2-POSITION, AND DYES CONTAINING THESE COMPOUNDS | Wella Aktiengesellschaft (DE) | 2005-01-12 | — | — | EP | claimed |
| US-20040147515-A1 | 3-Aminophenol derivatives substituted in the 2-position, and dyes containing these compounds | WELLA AKTIENGESELLSCHAFT (DE) | 2004-07-29 | — | — | US | claimed |
| WO-2003087034-A1 | 3-AMINOPHENOL DERIVATIVES SUBSTITUTED IN THE 2-POSITION, AND DYES CONTAINING THESE COMPOUNDS | WELLA AKTIENGESELLSCHAFT (DE) | 2003-10-23 | — | — | WO | claimed |
| EP-1494995-B1 | 3-AMINOPHENOL DERIVATIVES SUBSTITUTED IN THE 2-POSITION, AND DYES CONTAINING THESE COMPOUNDS | PROCTER & GAMBLE (US) | 2010-09-22 | — | — | EP | disclosed |
| US-7033401-B2 | 3-Aminophenol derivatives substituted in the 2-position, and dyes containing these compounds | WELLA AG (DE) | 2006-04-25 | — | — | US | disclosed |
| CN-1646478-A | 3-aminophenol derivatives substituted in the 2-position and colorants comprising the same | P & G CLAIROL INC (US) | 2005-07-27 | — | — | CN | disclosed |
| EP-1494995-A1 | 3-AMINOPHENOL DERIVATIVES SUBSTITUTED IN THE 2-POSITION, AND DYES CONTAINING THESE COMPOUNDS | Wella Aktiengesellschaft (DE) | 2005-01-12 | — | — | EP | disclosed |
| US-20040147515-A1 | 3-Aminophenol derivatives substituted in the 2-position, and dyes containing these compounds | WELLA AKTIENGESELLSCHAFT (DE) | 2004-07-29 | — | — | US | disclosed |
| WO-2003087034-A1 | 3-AMINOPHENOL DERIVATIVES SUBSTITUTED IN THE 2-POSITION, AND DYES CONTAINING THESE COMPOUNDS | WELLA AKTIENGESELLSCHAFT (DE) | 2003-10-23 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040147515-A1 | 3-Aminophenol derivatives substituted in the 2-position, and dyes containing these compounds | ALPP, TYR, RB1 | GAPDH 463/4885MEN1 4158/4885KMT2A 1774/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.