Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5 | P09917 | 1/20 | 0.54 |
| ▸ | CNR2 | P34972 | 1/20 | 0.51 |
| ▸ | RAB9A | P51151 | 5/20 | 0.45 |
| ▸ | MAPT | P10636 | 4/20 | 0.45 |
| ▸ | NPC1 | O15118 | 4/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.45 |
| ▸ | TP53 | P04637 | 2/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | USP2 | O75604 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.45 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.45 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.45 |
| ▸ | NR0B1 | P51843 | 1/20 | 0.45 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | RELA | Q04206 | 1/20 | 0.45 |
| ▸ | CD274 | Q9NZQ7 | 7/20 | 0.43 |
| ▸ | PDCD1 | Q15116 | 5/20 | 0.43 |
| ▸ | HSP90AA1 | P07900 | 2/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL2939395 | 0.98 | ALOX5 (0.53) | ALOX5CNR2RAB9AMAPTNPC1 | |
| SCHEMBL2934537 | 0.91 | GAPDH (0.49) | ALOX5CNR2MAPTMEN1LMNA | |
| Hydrochloric Acid SCHEMBL2933346 | 0.89 | GAPDH (0.48) | ALOX5CNR2MAPTMEN1LMNA | |
| SCHEMBL2939433 | 0.84 | DYRK1A (0.51) | RAB9AMAPTNPC1SMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL2939520 | 0.82 | FABP4 (0.50) | RAB9AMAPTNPC1SMN1; SMN2 | |
| SCHEMBL2937981 | 0.74 | ALDH1A1 (0.57) | MAPTSMN1; SMN2MEN1USP2LMNA | |
| SCHEMBL2937944 | 0.74 | APP (0.54) | ALOX5MAPTMEN1USP2LMNA | |
| SCHEMBL2938310 | 0.74 | MEN1 (0.50) | MAPTSMN1; SMN2MEN1USP2LMNA | |
| SCHEMBL657415 | 0.73 | CD274 (0.54) | ALOX5RAB9AMAPTNPC1SMN1; SMN2 | |
| SCHEMBL28076731 | 0.73 | MAPT (0.63) | ALOX5CNR2RAB9AMAPTNPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1494995-B1 | 3-AMINOPHENOL DERIVATIVES SUBSTITUTED IN THE 2-POSITION, AND DYES CONTAINING THESE COMPOUNDS | PROCTER & GAMBLE (US) | 2010-09-22 | — | — | EP | claimed |
| US-7033401-B2 | 3-Aminophenol derivatives substituted in the 2-position, and dyes containing these compounds | WELLA AG (DE) | 2006-04-25 | — | — | US | claimed |
| EP-1494995-A1 | 3-AMINOPHENOL DERIVATIVES SUBSTITUTED IN THE 2-POSITION, AND DYES CONTAINING THESE COMPOUNDS | Wella Aktiengesellschaft (DE) | 2005-01-12 | — | — | EP | claimed |
| US-20040147515-A1 | 3-Aminophenol derivatives substituted in the 2-position, and dyes containing these compounds | WELLA AKTIENGESELLSCHAFT (DE) | 2004-07-29 | — | — | US | claimed |
| WO-2003087034-A1 | 3-AMINOPHENOL DERIVATIVES SUBSTITUTED IN THE 2-POSITION, AND DYES CONTAINING THESE COMPOUNDS | WELLA AKTIENGESELLSCHAFT (DE) | 2003-10-23 | — | — | WO | claimed |
| EP-1494995-B1 | 3-AMINOPHENOL DERIVATIVES SUBSTITUTED IN THE 2-POSITION, AND DYES CONTAINING THESE COMPOUNDS | PROCTER & GAMBLE (US) | 2010-09-22 | — | — | EP | disclosed |
| US-7033401-B2 | 3-Aminophenol derivatives substituted in the 2-position, and dyes containing these compounds | WELLA AG (DE) | 2006-04-25 | — | — | US | disclosed |
| EP-1494995-A1 | 3-AMINOPHENOL DERIVATIVES SUBSTITUTED IN THE 2-POSITION, AND DYES CONTAINING THESE COMPOUNDS | Wella Aktiengesellschaft (DE) | 2005-01-12 | — | — | EP | disclosed |
| US-20040147515-A1 | 3-Aminophenol derivatives substituted in the 2-position, and dyes containing these compounds | WELLA AKTIENGESELLSCHAFT (DE) | 2004-07-29 | — | — | US | disclosed |
| WO-2003087034-A1 | 3-AMINOPHENOL DERIVATIVES SUBSTITUTED IN THE 2-POSITION, AND DYES CONTAINING THESE COMPOUNDS | WELLA AKTIENGESELLSCHAFT (DE) | 2003-10-23 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040147515-A1 | 3-Aminophenol derivatives substituted in the 2-position, and dyes containing these compounds | ALPP, TYR, RB1 | ALOX5 3104/4885CNR2 1600/4885RAB9A 4536/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.