Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | DTYMK | P23919 | 1/20 | 0.42 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.41 |
| ▸ | AKR1C4 | P17516 | 1/20 | 0.41 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.41 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.41 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | TTR | P02766 | 1/20 | 0.40 |
| ▸ | PPOX | P50336 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | IGF1R | P08069 | 1/20 | 0.39 |
| ▸ | EIF4E | P06730 | 4/20 | 0.38 |
| ▸ | CDK2 | P24941 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | TAS2R14 | Q9NYV8 | 1/20 | 0.36 |
| ▸ | HPD | P32754 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2934012 | 0.84 | TUBB4A (0.45) | LMNAMAPTHTTKMT2ATDP1 | |
| SCHEMBL27723772 | 0.81 | DTYMK (0.42) | LMNAMAPTHTTDTYMKMEN1 | |
| SCHEMBL2933943 | 0.78 | ALDH1A1 (0.47) | MAPTMEN1KMT2ATDP1TAS2R14 | |
| SCHEMBL535729 | 0.74 | IGF1R (0.39) | LMNAMAPTHTTMEN1KMT2A | |
| SCHEMBL2935943 | 0.71 | PKM (0.51) | LMNAMAPTHTTIGF1RCDK2 | |
| SCHEMBL11697530 | 0.71 | DTYMK (0.60) | LMNAMAPTDTYMKTDP1TSHR | |
| SCHEMBL11581177 | 0.71 | CDK2 (0.55) | MAPTDTYMKAKR1C3AKR1C2MEN1 | |
| SCHEMBL29518583 | 0.70 | SMN1; SMN2 (0.51) | MEN1KMT2ATDP1ALDH1A1 | |
| SCHEMBL30586433 | 0.70 | ALDH1A1 (0.49) | MAPTHTTMEN1TTRKMT2A | |
| SCHEMBL16031334 | 0.70 | TTR (0.64) | LMNAMAPTHTTDTYMKAKR1B1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8580785-B2 | Insecticides | SYNGENTA CROP PROTECTION LLC (US) | 2013-11-12 | — | — | US | disclosed |
| US-8580785-B2 | Insecticides | SYNGENTA CROP PROTECTION LLC (US) | 2013-11-12 | — | — | US | disclosed |
| US-8580785-B2 | Insecticides | SYNGENTA CROP PROTECTION LLC (US) | 2013-11-12 | — | — | US | disclosed |
| EP-1919903-B1 | BICYCLIC BISAMIDE DERIVATIVES AND USE THEREOF AS INSECTICIDES | SYNGENTA PARTICIPATIONS AG (CH) | 2010-01-27 | — | — | EP | disclosed |
| EP-1919903-B1 | BICYCLIC BISAMIDE DERIVATIVES AND USE THEREOF AS INSECTICIDES | SYNGENTA PARTICIPATIONS AG (CH) | 2010-01-27 | — | — | EP | disclosed |
| US-20090221587-A1 | NOVEL INSECTICIDES | SYNGENTA CROP PROTECTION, INC. (US) | 2009-09-03 | — | — | US | disclosed |
| US-20090221587-A1 | NOVEL INSECTICIDES | SYNGENTA CROP PROTECTION, INC. (US) | 2009-09-03 | — | — | US | disclosed |
| US-20090221587-A1 | NOVEL INSECTICIDES | SYNGENTA CROP PROTECTION, INC. (US) | 2009-09-03 | — | — | US | disclosed |
| EP-1919903-A2 | BICYCLIC BISAMIDE DERIVATIVES AND USE THEREOF AS INSECTICIDES | Syngeta Participations AG (CH) | 2008-05-14 | — | — | EP | disclosed |
| WO-2007020050-A2 | BICYCLIC BISAMIDE DERIVATIVES AND USE THEREOF AS INSECTICIDES | SYNGENTA PARTICIPATIONS AG (CH) | 2007-02-22 | — | — | WO | disclosed |
| WO-2007020050-A2 | BICYCLIC BISAMIDE DERIVATIVES AND USE THEREOF AS INSECTICIDES | SYNGENTA PARTICIPATIONS AG (CH) | 2007-02-22 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090221587-A1 | NOVEL INSECTICIDES | DDT, CYP4F11, ACHE | LMNA 2246/4885MAPT 64/4885HTT 2615/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.