Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PKM | P14618 | 1/20 | 0.51 |
| ▸ | PDE4B | Q07343 | 7/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | IGF1R | P08069 | 3/20 | 0.37 |
| ▸ | LMNA | P02545 | 2/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | TPMT | P51580 | 1/20 | 0.34 |
| ▸ | PDE4A | P27815 | 3/20 | 0.34 |
| ▸ | PDE4C | Q08493 | 3/20 | 0.34 |
| ▸ | PDE4D | Q08499 | 3/20 | 0.34 |
| ▸ | CDK2 | P24941 | 2/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
| ▸ | NT5E | P21589 | 1/20 | 0.34 |
| ▸ | PDE11A | Q9HCR9 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2938117 | 0.90 | TUBB4A (0.42) | PKMPDE4BALDH1A1IGF1RLMNA | |
| SCHEMBL535729 | 0.84 | IGF1R (0.39) | PKMPDE4BALDH1A1IGF1RLMNA | |
| SCHEMBL2936513 | 0.82 | PDE4B (0.41) | PDE4BALDH1A1IGF1RPDE4APDE4C | |
| SCHEMBL13697803 | 0.80 | PDE4B (0.41) | PDE4BALDH1A1IGF1RPDE4APDE4C | |
| SCHEMBL535642 | 0.80 | SDHB (0.37) | PKMALDH1A1IGF1RMAPTPDE4A | |
| SCHEMBL535545 | 0.77 | TUBB4A (0.40) | PDE4BALDH1A1IGF1RLMNAMAPT | |
| SCHEMBL535887 | 0.77 | TUBB4A (0.40) | PDE4BALDH1A1IGF1RLMNAMAPT | |
| SCHEMBL2934757 | 0.71 | LMNA (0.42) | ALDH1A1IGF1RLMNAMAPTHTT | |
| SCHEMBL3633692 | 0.70 | KDM4E (0.36) | ALDH1A1IGF1RLMNAMAPTHTT | |
| SCHEMBL535644 | 0.70 | GABRP (0.39) | PDE4BALDH1A1LMNAKDM4EHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8580785-B2 | Insecticides | SYNGENTA CROP PROTECTION LLC (US) | 2013-11-12 | — | — | US | disclosed |
| US-8580785-B2 | Insecticides | SYNGENTA CROP PROTECTION LLC (US) | 2013-11-12 | — | — | US | disclosed |
| US-8580785-B2 | Insecticides | SYNGENTA CROP PROTECTION LLC (US) | 2013-11-12 | — | — | US | disclosed |
| EP-1919903-B1 | BICYCLIC BISAMIDE DERIVATIVES AND USE THEREOF AS INSECTICIDES | SYNGENTA PARTICIPATIONS AG (CH) | 2010-01-27 | — | — | EP | disclosed |
| EP-1919903-B1 | BICYCLIC BISAMIDE DERIVATIVES AND USE THEREOF AS INSECTICIDES | SYNGENTA PARTICIPATIONS AG (CH) | 2010-01-27 | — | — | EP | disclosed |
| US-20090221587-A1 | NOVEL INSECTICIDES | SYNGENTA CROP PROTECTION, INC. (US) | 2009-09-03 | — | — | US | disclosed |
| US-20090221587-A1 | NOVEL INSECTICIDES | SYNGENTA CROP PROTECTION, INC. (US) | 2009-09-03 | — | — | US | disclosed |
| US-20090221587-A1 | NOVEL INSECTICIDES | SYNGENTA CROP PROTECTION, INC. (US) | 2009-09-03 | — | — | US | disclosed |
| EP-1919903-A2 | BICYCLIC BISAMIDE DERIVATIVES AND USE THEREOF AS INSECTICIDES | Syngeta Participations AG (CH) | 2008-05-14 | — | — | EP | disclosed |
| WO-2007020050-A2 | BICYCLIC BISAMIDE DERIVATIVES AND USE THEREOF AS INSECTICIDES | SYNGENTA PARTICIPATIONS AG (CH) | 2007-02-22 | — | — | WO | disclosed |
| WO-2007020050-A2 | BICYCLIC BISAMIDE DERIVATIVES AND USE THEREOF AS INSECTICIDES | SYNGENTA PARTICIPATIONS AG (CH) | 2007-02-22 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090221587-A1 | NOVEL INSECTICIDES | DDT, CYP4F11, ACHE | PKM 1825/4885PDE4B 1031/4885ALDH1A1 142/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.