SCHEMBL2934814

SCHEMBL2934814

Fc1cc(F)c(I)cc1F

nearest known ligand 0.31

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
GPR84 Q9NQS5 1/20 0.31
CA1 P00915 1/20 0.30
CA2 P00918 1/20 0.30
CA3 P07451 1/20 0.30
CA9 Q16790 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30096741 1.00 GPR84 (0.31) GPR84CA1CA2CA3CA9
SCHEMBL14129494 0.93 CA1 (0.32) CA1CA2CA3CA9
SCHEMBL19001649 0.89 CA1 (0.31) CA1CA2CA3CA9
SCHEMBL4138790 0.85 GPR84 (0.33) GPR84CA1CA2CA3CA9
SCHEMBL1191944 0.76 KDM1A (0.34) CA1CA2CA3CA9
SCHEMBL12583448 0.76 TTR (0.33)
SCHEMBL21614392 0.76 CA3 (0.40) CA1CA2CA3CA9
SCHEMBL20828625 0.76
SCHEMBL12378577 0.76 ALDH1A1 (0.43) GPR84
SCHEMBL5174339 0.76 KDM1A (0.39) CA1CA2CA3CA9

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 44 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-102153559-B Method for synthesizing sitagliptin phosphate and derivatives thereof NANJING UNIVERSITY OF TECHNOLOGY 2013-04-24 CN claimed
CN-102153559-A Novel method for synthesizing sitagliptin phosphate and derivatives thereof NANJING UNIVERSITY OF TECHNOLOGY 2011-08-17 CN claimed
EP-1362860-B1 Method for producing tetrakis (fluoraryl)borate magnesium compound NIPPON CATALYTIC CHEM IND (JP) 2010-09-15 EP claimed
US-7205441-B2 Method for producing tetrakis (fluoroaryl) borate-magnesium compound NIPPON SHOKUBAI CO., LTD. (JP) 2007-04-17 US claimed
US-20030216598-A1 Method for producing tetrakis ( fluoroaryl) borate-magnesium compound NIPPON SHOKUBAI CO., LTD. (JP) 2003-11-20 US claimed
EP-1362860-A1 Method for producing tetrakis (fluoroaryl) borate magnesium compound Nippon Shokubai Co., Ltd. (JP) 2003-11-19 EP claimed
CN-119604290-A Compounds for the treatment of coronavirus infections 特劳斯芬尼德治疗股份有限公司 2025-03-11 CN disclosed
EP-4186892-A1 NOVEL COMPOUND, COATING COMPOSITION COMPRISING SAME, ORGANIC LIGHT-EMITTING DEVICE USING SAME, AND MANUFACTURING METHOD THEREFOR Lg Chem, Ltd. (KR) 2023-05-31 EP disclosed
US-20220402881-A1 SMALL MOLECULE PROSTAGLADIN TRANSPORT INHIBITORS ALBERT EINSTEIN COLLEGE OF MEDICINE 2022-12-22 US disclosed
CN-115385919-A Synthetic method of sitagliptin 江苏阿尔法药业股份有限公司 2022-11-25 CN disclosed
EP-3954677-A1 NOVEL COMPOUND AND ORGANIC LIGHT EMITTING DEVICE COMPRISING SAME LG Chem, Ltd. (KR) 2022-02-16 EP disclosed
WO-2021015522-A1 NOVEL COMPOUND AND ORGANIC LIGHT EMITTING DEVICE COMPRISING SAME 주식회사 엘지화학 2021-01-28 WO disclosed
EP-3237416-B1 POLYCYCLIC-CARBAMOYLPYRIDONE COMPOUNDS AND THEIR PHARMACEUTICAL USE GILEAD SCIENCES INC (US) 2019-05-01 EP disclosed
EP-1211255-A2 Method for producing fluoroaryl metal compound Nippon Shokubai Co., Ltd. (JP) 2002-06-05 EP disclosed
US-20020065426-A1 Method for producing fluoroaryl metal compound NIPPON SHOKUBAI CO., LTD (JP) 2002-05-30 US disclosed
US-6235222-B1 REACTING, IN SOLVENT CONTAINING CHAIN ETHER SOLVENT, HYDROCARBON MAGNESIUM HALIDE WITH FLUOROARYL HALIDE NIPPON SHOKUBAI CO., LTD. (JP) 2001-05-22 US disclosed
EP-0995753-A2 Method for manufacturing fluoroaryl magnesium halide Nippon Shokubai Co., Ltd. (JP) 2000-04-26 EP disclosed
EP-0109606-B1 PROCESS FOR THE FORMYLATION OF ARYL HALIDES BAYER AG (DE) 1986-01-22 EP disclosed
US-4536344-A USING A PHOSPINE OR PHOSPHITE BAYER AKTIENGESELLSCHAFT (DE) 1985-08-20 US disclosed
EP-0109606-A1 Process for the formylation of aryl halides BAYER AG (DE) 1984-05-30 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20030216598-A1 Method for producing tetrakis ( fluoroaryl) borate-magnesium compound KRAS, MGAM, CA3 GPR84 3052/4885CA1 190/4885CA2 119/4885
US-20220402881-A1 SMALL MOLECULE PROSTAGLADIN TRANSPORT INHIBITORS PTGER1, PTGIS, PTGIR GPR84 482/4885CA1 2453/4885CA2 526/4885
US-20020065426-A1 Method for producing fluoroaryl metal compound DDT, TERT, HACL2 GPR84 3724/4885CA1 3552/4885CA2 2403/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.