Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABCG2 | Q9UNQ0 | 7/20 | 1.00 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.90 |
| ▸ | DPP4 | P27487 | 1/20 | 0.90 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.90 |
| ▸ | RELA | Q04206 | 1/20 | 0.90 |
| ▸ | MAPT | P10636 | 6/20 | 0.82 |
| ▸ | CYP3A4 | P08684 | 6/20 | 0.82 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.82 |
| ▸ | TP53 | P04637 | 2/20 | 0.82 |
| ▸ | ATM | Q13315 | 1/20 | 0.82 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.82 |
| ▸ | MKNK2 | Q9HBH9 | 1/20 | 0.81 |
| ▸ | MEN1 | O00255 | 4/20 | 0.81 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.81 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.81 |
| ▸ | HPGD | P15428 | 2/20 | 0.81 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.81 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.81 |
| ▸ | USP2 | O75604 | 1/20 | 0.81 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.81 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Flavokawain A SCHEMBL25209870 | 1.00 | ABCG2 (1.00) | ABCG2NFKB1DPP4NFKB2RELA | |
| Flavokawain A SCHEMBL2289181 | 1.00 | ABCG2 (1.00) | ABCG2NFKB1DPP4NFKB2RELA | |
| Flavokawain A SCHEMBL2289188 | 1.00 | ABCG2 (1.00) | ABCG2NFKB1DPP4NFKB2RELA | |
| Flavokawain C SCHEMBL30384247 | 0.94 | NFKB1 (1.00) | ABCG2NFKB1DPP4NFKB2RELA | |
| Flavokawain C SCHEMBL25201341 | 0.94 | NFKB1 (1.00) | ABCG2NFKB1DPP4NFKB2RELA | |
| Flavokawain C SCHEMBL144230 | 0.94 | NFKB1 (1.00) | ABCG2NFKB1DPP4NFKB2RELA | |
| Flavokawain C SCHEMBL144231 | 0.94 | NFKB1 (1.00) | ABCG2NFKB1DPP4NFKB2RELA | |
| SCHEMBL30383887 | 0.93 | ABCG2 (0.87) | ABCG2NFKB1DPP4NFKB2RELA | |
| SCHEMBL2286230 | 0.93 | ABCG2 (0.87) | ABCG2NFKB1DPP4NFKB2RELA | |
| SCHEMBL2286236 | 0.93 | ABCG2 (0.87) | ABCG2NFKB1DPP4NFKB2RELA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 210 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20260048027-A1 | METHYLATED PHLORETIN ANALOGS AS INHIBITORS OF SGLT2 | NESTLE SA (CH) | 2026-02-19 | — | — | US | claimed |
| US-20260014100-A1 | Compositions and Methods for Treating Bleeding and Bleeding Disorders | YEWSAVIN INC (US) | 2026-01-15 | — | — | US | claimed |
| US-12419927-B2 | Kava compositions and methods of use | BOTANIC TONICS LLC (US) | 2025-09-23 | — | — | US | claimed |
| US-20250213637-A1 | KAVA DERIVED THERAPEUTIC COMPOUNDS AND METHODS OF USE THEREOF | KUALITY HERBCEUTICS LLC (US) | 2025-07-03 | — | — | US | claimed |
| EP-4572749-A1 | METHYLATED PHLORETIN ANALOGS AS INHIBITORS OF SGLT2 | Société des Produits Nestlé S.A. (CH) | 2025-06-25 | — | — | EP | claimed |
| US-20250090565-A1 | Compositions and Methods for Treating Bleeding and Bleeding Disorders | YewSavin, Inc. (US) | 2025-03-20 | — | — | US | claimed |
| WO-2024233598-A1 | COMPOSITIONS AND METHODS FOR TREATING BLEEDING AND BLEEDING DISORDERS | YewSavin, Inc. (US) | 2024-11-14 | — | — | WO | claimed |
| CN-118754832-A | Chalcone and flavanone sulfonamide derivative, and synthetic method and application thereof | 郑州大学 | 2024-10-11 | — | — | CN | claimed |
| EP-4429763-A1 | COMPOSITIONS AND METHODS FOR TREATING BLEEDING AND BLEEDING DISORDERS | Yewsavin, Inc. (US) | 2024-09-18 | — | — | EP | claimed |
| CN-118416231-A | New use of Neddylination inhibitor in promoting osteoblast differentiation | 首都医科大学 | 2024-08-02 | — | — | CN | claimed |
| EP-3391880-B1 | NEDDYLATION INHIBITOR FOR USE IN PREVENTING OR TREATING OSTEOPOROSIS | UNIV CHANG GUNG (TW) | 2023-06-07 | — | — | EP | claimed |
| WO-2023086388-A1 | COMPOSITIONS AND METHODS FOR TREATING BLEEDING AND BLEEDING DISORDERS | YewSavin, Inc. (US) | 2023-05-19 | — | — | WO | claimed |
| US-20230105013-A1 | Isolated or Engineered Polypeptides, Microorganisms as well as Method for Synthesizing Phenolic Phytochemical Phosphate Derivatives using the Polypeptides or Microorganisms | NATIONAL TAIWAN UNIVERSITY (TW) | 2023-04-06 | — | — | US | claimed |
| US-20230057309-A1 | Inhibitors of DREAM Complex Assembly and/or Function For Use In Repairing DNA Damage | H. LEE MOFFITT CANCER CENTER AND RESEARCH INSTITUTE, INC. | 2023-02-23 | — | — | US | claimed |
| EP-4091610-A1 | INHIBITORS OF DREAM COMPLEX ASSEMBLY AND/OR FUNCTION FOR USE IN REPAIRING DNA DAMAGE | Schumacher, Björn (DE) | 2022-11-23 | — | — | EP | claimed |
| EP-4091611-A1 | INHIBITORS OF DREAM COMPLEX ASSEMBLY AND/OR FUNCTION FOR USE IN REPAIRING DNA DAMAGE | Schumacher, Björn (DE) | 2022-11-23 | — | — | EP | claimed |
| CN-114931566-A | Application of kava piperine A in preparation of medicine for treating pulmonary fibrosis | 天津济坤医药科技有限公司 | 2022-08-23 | — | — | CN | claimed |
| WO-2022081889-A1 | METHOD AND SYSTEMS FOR PHYTOMEDICINE ANALYTICS FOR RESEARCH OPTIMIZATION AT SCALE | GBS GLOBAL BIOPHARMA, INC. (CA) | 2022-04-21 | — | — | WO | claimed |
| WO-2022056252-A1 | COMPOSITIONS AND METHODS FOR TREATING HYPERGLYCEMIA IN TYPE-2 DIABETES | THE BOARD OF REGENTS OF THE UNIVERSITY OF OKLAHOMA (US) | 2022-03-17 | — | — | WO | claimed |
| CN-113956226-A | Method for synthesizing carvachin | 南京科技职业学院 | 2022-01-21 | — | — | CN | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20260014100-A1 | Compositions and Methods for Treating Bleeding and Bleeding Disorders | SERPINC1, F2, F13B | ABCG2 1606/4885NFKB1 1669/4885DPP4 4226/4885 |
| US-20250213637-A1 | KAVA DERIVED THERAPEUTIC COMPOUNDS AND METHODS OF USE THEREOF | KLK5, KLK4, KLK2 | ABCG2 3744/4885NFKB1 2049/4885DPP4 3685/4885 |
| US-20260048027-A1 | METHYLATED PHLORETIN ANALOGS AS INHIBITORS OF SGLT2 | SLC5A2, SLC5A1, SLC2A1 | ABCG2 954/4885NFKB1 4036/4885DPP4 302/4885 |
| US-20250090565-A1 | Compositions and Methods for Treating Bleeding and Bleeding Disorders | SERPINC1, TFPI, SERPINE1 | ABCG2 3458/4885NFKB1 2413/4885DPP4 3437/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.