SCHEMBL29350754

SCHEMBL29350754

COc1cc(Nc2ccc([N+](=O)[O-])cc2C(=O)O)cc2ccccc12

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ ANO1 Q5XXA6 1/20 1.00
▸ ANO2 Q9NQ90 1/20 1.00
▸ CTSV O60911 3/20 0.63
▸ CTSL P07711 3/20 0.63
▸ MAPT P10636 5/20 0.56
▸ MEN1 O00255 5/20 0.56
▸ KMT2A Q03164 5/20 0.56
▸ MYC P01106 1/20 0.52
▸ MAX P61244 1/20 0.52
▸ LMNA P02545 2/20 0.51
▸ POLB P06746 1/20 0.51
▸ MAPK1 P28482 1/20 0.51
▸ AKR1C3 P42330 4/20 0.49
▸ AKR1C2 P52895 4/20 0.49
▸ GAA P10253 2/20 0.48
▸ ALDH1A1 P00352 2/20 0.47
▸ SMN1; SMN2 Q16637 2/20 0.47
▸ CRHBP P24387 1/20 0.47
▸ HTT P42858 1/20 0.47
▸ CRHR2 Q13324 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16737209 1.00 ANO1 (1.00) ANO1ANO2CTSVCTSLMAPT
SCHEMBL16737120 0.92 ANO1 (0.84) ANO1ANO2CTSVCTSLMAPT
SCHEMBL16737098 0.88 ANO1 (0.79) ANO1ANO2CTSVCTSLMAPT
SCHEMBL16737100 0.84 ANO1 (0.72) ANO1ANO2CTSVCTSLMAPT
SCHEMBL16737170 0.84 ANO1 (0.72) ANO1ANO2CTSVCTSLMAPT
SCHEMBL16737203 0.84 ANO1 (0.72) ANO1ANO2CTSVCTSLMAPT
SCHEMBL16737099 0.83 ANO1 (0.71) ANO1ANO2CTSVCTSLMAPT
SCHEMBL16737089 0.82 ANO1 (0.70) ANO1ANO2CTSVCTSLMAPT
SCHEMBL16737168 0.82 ANO1 (0.70) ANO1ANO2CTSVCTSLMAPT
SCHEMBL16737171 0.82 CDC25B (0.69) ANO1ANO2CTSVCTSLMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 84 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250312336-A1 Compositions And Methods For Treating Cancer With Calcium Channel Inhibitors INSTITUTE FOR CANCER RES D/B/A THE RES INSTITUTE OF FOX CHASE CANCER CENTER (US) 2025-10-09 — — US claimed
US-20240122922-A1 Methods Of Treating Cancer With Transmembrane Protein 16F (TMEM16F) Inhibitors NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT 2024-04-18 — — US claimed
US-20260109872-A1 Ink Jet Ink Composition And Ink Jet Recording Method SEIKO EPSON CORP (JP) 2026-04-23 — — US disclosed
US-20260071230-A1 Precise Bioengineering Of Flowering Time For Bioenergy Production And Gene Containment U.S. DEPARTMENT OF ENERGY 2026-03-12 — — US disclosed
EP-4707350-A1 TREATMENT LIQUID COMPOSITION FOR DYE PRINTING, INK SET, AND RECORDING METHOD Seiko Epson Corporation (JP) 2026-03-11 — — EP disclosed
EP-4484154-B1 GARMENT FABRIC AND GARMENT FABRIC MANUFACTURING METHOD SEIKO EPSON CORP (JP) 2026-01-21 — — EP disclosed
US-20250389081-A1 Treatment Liquid Composition For Dye Printing, Ink Set, And Recording Method SEIKO EPSON CORP (JP) 2025-12-25 — — US disclosed
US-12492403-B2 Aptamers and the use thereof in the treatment of cancer FUNDACIÓN PARA LA INVESTIGACIÓN BIOMÉDICA DEL HOSPITAL RAMÓN Y CAJAL (ES) 2025-12-09 — — US disclosed
US-12486415-B2 Ink jet textile-printing ink composition, recording method, and recorded material SEIKO EPSON CORPORATION (JP) 2025-12-02 — — US disclosed
EP-4637541-A1 DEVICE, SYSTEM AND METHOD FOR MONITORING A SITE OF INTEREST INTERNAL TO A PATIENT BODY Exero Medical Ltd. (IL) 2025-10-29 — — EP disclosed
US-20250312336-A1 Compositions And Methods For Treating Cancer With Calcium Channel Inhibitors INSTITUTE FOR CANCER RES D/B/A THE RES INSTITUTE OF FOX CHASE CANCER CENTER (US) 2025-10-09 — — US disclosed
CN-114318909-A Printing method, printed matter, and recording apparatus 精工爱普生株式会社 2022-04-12 — — CN disclosed
EP-3978680-A1 TEXTILE PRINTING METHOD, PRINTED MATTER, AND RECORDING APPARATUS Seiko Epson Corporation (JP) 2022-04-06 — — EP disclosed
US-20220097435-A1 Textile Printing Method, Printed Matter, And Recording Apparatus SEIKO EPSON CORPORATION (JP) 2022-03-31 — — US disclosed
CN-109628469-B Molecular marker for identifying barley half-dwarf multi-tillering gene Hvhtd based on intron 2 and application thereof 浙江省农业科学院 2022-03-29 — — CN disclosed
CN-111279300-B Providing a rich electronic reading experience in a multi-display environment 华为技术有限公司 2022-03-29 — — CN disclosed
US-11274074-B2 Pharmaceutical composition for ANO1 antagonist with anticancer activity INDUSTRY-ACADEMIC COOPERATION FOUNDATION YONSEI UNIVERSITY (KR) 2022-03-15 — — US disclosed
CN-109321037-B Ink for ink jet textile printing and ink set for ink jet textile printing 精工爱普生株式会社 2022-02-15 — — CN disclosed
US-20220042018-A1 APTAMERS AND THE USE THEREOF IN THE TREATMENT OF CANCER FUNDACIÓN PARA LA INVESTIGACIÓN BIOMÉDICA DEL HOSPITAL RAMÓN Y CAJAL (ES) 2022-02-10 — — US disclosed
CN-110136087-B Self-adaptive frame adjusting method of display terminal and related equipment 京东方艺云科技有限公司 2022-01-25 — — CN disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11274074-B2 Pharmaceutical composition for ANO1 antagonist with anticancer activity ANO1, ANO2, TMEM109 ANO1 1/4885ANO2 2/4885CTSV 3807/4885
US-20250389081-A1 Treatment Liquid Composition For Dye Printing, Ink Set, And Recording Method SORD, ME1, G6PD ANO1 299/4885ANO2 500/4885CTSV 4457/4885
US-20260109872-A1 Ink Jet Ink Composition And Ink Jet Recording Method COPE, EED, VCL ANO1 2973/4885ANO2 3623/4885CTSV 3767/4885
US-20260071230-A1 Precise Bioengineering Of Flowering Time For Bioenergy Production And Gene Containment STARD10, ZMYND8, OSBPL8 ANO1 3757/4885ANO2 3791/4885CTSV 3210/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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