Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR6 | P50406 | 1/20 | 0.51 |
| ▸ | ACLY | P53396 | 1/20 | 0.46 |
| ▸ | KAT6A | Q92794 | 1/20 | 0.44 |
| ▸ | ITGAV | P06756 | 1/20 | 0.43 |
| ▸ | SLC40A1 | Q9NP59 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | SLC22A12 | Q96S37 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | PKM | P14618 | 1/20 | 0.40 |
| ▸ | PTPN2 | P17706 | 1/20 | 0.40 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.40 |
| ▸ | PTPN5 | P54829 | 1/20 | 0.40 |
| ▸ | BRD4 | O60885 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | ALPL | P05186 | 1/20 | 0.39 |
| ▸ | RAD52 | P43351 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18726068 | 1.00 | HTR6 (0.51) | HTR6ACLYKAT6AITGAVSLC40A1 | |
| SCHEMBL29350506 | 0.84 | ALPL (0.52) | SMN1; SMN2TSHRPKMALPL | |
| SCHEMBL18726025 | 0.84 | ALPL (0.52) | SMN1; SMN2TSHRPKMALPL | |
| SCHEMBL3575927 | 0.83 | HTR6 (0.53) | HTR6ACLYKAT6AITGAVSLC40A1 | |
| SCHEMBL18757918 | 0.78 | ALDH1A1 (0.37) | SMN1; SMN2PKMALDH1A1RAD52 | |
| SCHEMBL24429401 | 0.77 | PARG (0.48) | HTR6ACLYKAT6AITGAVSLC40A1 | |
| SCHEMBL14680691 | 0.76 | KAT6A (0.49) | HTR6ACLYKAT6AITGAVSLC40A1 | |
| SCHEMBL29965203 | 0.75 | L3MBTL1 (0.61) | HTR6ACLYKAT6AITGAVSLC40A1 | |
| SCHEMBL6903823 | 0.75 | NR3C2 (0.53) | SMN1; SMN2NPC1ALDH1A1 | |
| SCHEMBL2371550 | 0.75 | L3MBTL1 (0.61) | HTR6ACLYKAT6AITGAVSLC40A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108368104-B | Novel compound inhibitors of the YAP/TAZ-TEAD interaction and their use in the treatment of malignant mesothelioma | 伊文蒂瓦公司 | 2022-01-21 | — | — | CN | disclosed |