Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CARM1 | Q86X55 | 3/20 | 0.36 |
| ▸ | PDE4B | Q07343 | 3/20 | 0.35 |
| ▸ | KLKB1 | P03952 | 3/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | F10 | P00742 | 2/20 | 0.35 |
| ▸ | F2 | P00734 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.34 |
| ▸ | KCNT1 | Q5JUK3 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL672741 | 0.92 | PDE4B (0.36) | CARM1PDE4BKLKB1KDM4EF10 | |
| SCHEMBL14360665 | 0.92 | KDM4E (0.37) | CARM1PDE4BKLKB1KDM4EMEN1 | |
| SCHEMBL14470584 | 0.91 | PDE4B (0.36) | CARM1PDE4BKLKB1KDM4EMEN1 | |
| SCHEMBL4082479 | 0.91 | CARM1 (0.40) | CARM1PDE4BKLKB1KDM4EL3MBTL1 | |
| SCHEMBL4491830 | 0.90 | PDE4B (0.35) | CARM1PDE4BKLKB1KDM4EF10 | |
| SCHEMBL782481 | 0.90 | DHODH (0.36) | CARM1PDE4BKLKB1KDM4EF10 | |
| SCHEMBL4478603 | 0.90 | PDE4B (0.38) | CARM1PDE4BKLKB1KDM4EF10 | |
| SCHEMBL4675046 | 0.90 | CARM1 (0.37) | CARM1PDE4BKLKB1F10 | |
| SCHEMBL29393434 | 0.89 | DHODH (0.39) | CARM1PDE4BKLKB1KDM4EMEN1 | |
| SCHEMBL1380391 | 0.89 | DHODH (0.39) | CARM1PDE4BKLKB1KDM4EMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7199138-B2 | Substituted anthranilamides for controlling invertebrate pests | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 2007-04-03 | — | — | US | claimed |
| US-20050282868-A1 | Substituted anthranilamides for controlling invertebrate pests | E. I. DU PONT DE NEMOURS AND COMPANY | 2005-12-22 | — | — | US | claimed |
| US-8658801-B2 | Pesticides containing a bicyclic bisamide structure | SYNGENTA CROP PROTECTION, LLC (US) | 2014-02-25 | — | — | US | disclosed |
| US-8580785-B2 | Insecticides | SYNGENTA CROP PROTECTION LLC (US) | 2013-11-12 | — | — | US | disclosed |
| EP-1919903-B1 | BICYCLIC BISAMIDE DERIVATIVES AND USE THEREOF AS INSECTICIDES | SYNGENTA PARTICIPATIONS AG (CH) | 2010-01-27 | — | — | EP | disclosed |
| US-20090298816-A1 | PESTICIDES CONTAINING A BICYCLIC BISAMIDE STRUCTURE | SYNGENTA CROP PROTECTION, INC. (US) | 2009-12-03 | — | — | US | disclosed |
| US-20090221587-A1 | NOVEL INSECTICIDES | SYNGENTA CROP PROTECTION, INC. (US) | 2009-09-03 | — | — | US | disclosed |
| EP-1984354-B1 | PESTICIDES CONTAINING A BICYCLIC BISAMIDE STRUCTURE | SYNGENTA PARTICIPATIONS AG (CH) | 2009-08-05 | — | — | EP | disclosed |
| US-7541377-B2 | Substituted anthranilamides for controlling invertebrate pests | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 2009-06-02 | — | — | US | disclosed |
| EP-1417176-B1 | SUBSTITUTED ANTHRANILAMIDES FOR CONTROLLING INVERTEBRATE PESTS | DU PONT (US) | 2008-12-17 | — | — | EP | disclosed |
| EP-1984354-A1 | PESTICIDES CONTAINING A BICYCLIC BISAMIDE STRUCTURE | Syngeta Participations AG (CH) | 2008-10-29 | — | — | EP | disclosed |
| US-20070203201-A1 | Substituted anthranilamides for controlling invertebrate pests | FINKELSTEIN BRUCE L | 2007-08-30 | — | — | US | disclosed |
| WO-2007093402-A1 | PESTICIDES CONTAINING A BICYCLIC BISAMIDE STRUCTURE | SYNGENTA PARTICIPATIONS AG (CH) | 2007-08-23 | — | — | WO | disclosed |
| US-7199138-B2 | Substituted anthranilamides for controlling invertebrate pests | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 2007-04-03 | — | — | US | disclosed |
| US-20050282868-A1 | Substituted anthranilamides for controlling invertebrate pests | E. I. DU PONT DE NEMOURS AND COMPANY | 2005-12-22 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090298816-A1 | PESTICIDES CONTAINING A BICYCLIC BISAMIDE STRUCTURE | DDT, ACHE, GAP43 | CARM1 669/4885PDE4B 1607/4885KLKB1 4802/4885 |
| US-20090221587-A1 | NOVEL INSECTICIDES | DDT, CYP4F11, ACHE | CARM1 1109/4885PDE4B 1031/4885KLKB1 4606/4885 |
| US-20070203201-A1 | Substituted anthranilamides for controlling invertebrate pests | ANTXR2, PRXL2A, F9 | CARM1 1314/4885PDE4B 811/4885KLKB1 4573/4885 |
| US-20050282868-A1 | Substituted anthranilamides for controlling invertebrate pests | ANTXR2, PRXL2A, F9 | CARM1 1357/4885PDE4B 828/4885KLKB1 4524/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.