SCHEMBL29352986

SCHEMBL29352986

O=C1[C@H](Cc2ccc(O)cc2)N2C(=O)CCN(C(=O)NCc3ccccc3)[C@H]2CN1Cc1cccc2ccccc12

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
CLPP Q16740 19/20 1.00
CTNNB1 P35222 2/20 1.00
TCF7 P36402 2/20 1.00
BCL9 O00512 1/20 1.00
TCF4 P15884 1/20 1.00
CREBBP Q92793 1/20 1.00

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19833048 1.00 CLPP (1.00) CLPPCTNNB1TCF7BCL9TCF4
SCHEMBL13744871 1.00 CLPP (1.00) CLPPCTNNB1TCF7BCL9TCF4
SCHEMBL4865605 1.00 CLPP (1.00) CLPPCTNNB1TCF7BCL9TCF4
SCHEMBL178745 1.00 CLPP (1.00) CLPPCTNNB1TCF7BCL9TCF4
SCHEMBL15677335 1.00 CLPP (1.00) CLPPCTNNB1TCF7BCL9TCF4
SCHEMBL4865597 1.00 CLPP (1.00) CLPPCTNNB1TCF7BCL9TCF4
SCHEMBL15677334 0.96 CLPP (1.00) CLPPCTNNB1TCF7BCL9TCF4
SCHEMBL18699677 0.96 CLPP (1.00) CLPPCTNNB1TCF7BCL9TCF4
SCHEMBL19833044 0.94 CLPP (0.92) CLPPCTNNB1TCF7BCL9TCF4
SCHEMBL20752946 0.94 CLPP (0.92) CLPPCTNNB1TCF7BCL9TCF4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 688 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2025251988-A9 REAGENT COMBINATION OR KIT FOR CONSTRUCTING EMBRYOID AND USE THEREOF 广州国家实验室 2026-05-15 WO claimed
US-20260125650-A1 METHODS AND COMPOSITIONS FOR GENERATING HEPATOCYTES TRAILHEAD BIOSYSTEMS INC (US) 2026-05-07 US claimed
US-12570956-B2 Efficient derivation of stable pluripotent bovine embryonic stem cells THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2026-03-10 US claimed
EP-4346928-B1 BIODEGRADABLE TISSUE SCAFFOLD WITH SECONDARY MATRIX TO HOST WEAKLY ADHERENT CELLS US HEALTH (US) 2026-01-14 EP claimed
WO-2025262235-A1 UNGULATE PLURIPOTENT STEM CELL CULTURE MEDIUM MEAT TOMORROW APS (DK) 2025-12-26 WO claimed
US-12503685-B2 Cortical interneurons and other neuronal cells produced by the directed differentiation of pluripotent and multipotent cells MEMORIAL SLOAN-KETTERING CANCER CENTER (US) 2025-12-23 US claimed
US-12486495-B2 Cardiac organoid, manufacturing method therefor, and method for evaluating drug toxicity by using same INDUSTRY-ACADEMIC COOPERATION FOUNDATION, YONSEI UNIVERSITY (KR) 2025-12-02 US claimed
EP-4627061-A1 CULTURE MEDIUM, COATING MATRIX AND METHOD FOR MATURING MIDBRAIN DOPAMINERGIC PROGENITOR CELLS Nuwacell Biotechnologies Co., Ltd. (CN) 2025-10-08 EP claimed
EP-4615506-A1 USE OF GSK-3 ACTIVATIOR TO MODULATE PROTEASOME ACTIVITY TO PREVENT AGEING ASSOCIATED CONDITIONS AND DISEASES Sahin, Fikret (TR) 2025-09-17 EP claimed
US-12391919-B2 Culture medium, coating matrix and method for maturing midbrain dopaminergic progenitor cells NUWACELL BIOTECHNOLOGIES CO., LTD. (CN) 2025-08-19 US claimed
WO-2022051847-A9 METHODS FOR GENERATING NEURAL PROGENITOR CELLS WITH A SPINAL CORD IDENTITY UNIVERSITY HEALTH NETWORK (CA) 2022-04-21 WO claimed
CN-114369577-A Cattle induced expansion pluripotent adult stem cell, line establishing method and culture solution 内蒙古大学 2022-04-19 CN claimed
CN-114369567-A Method for establishing bovine expanded pluripotent embryonic stem cells and culture solution 内蒙古大学 2022-04-19 CN claimed
WO-2022031952-A9 TREATMENTS FOR CANCERS HAVING KRAS MUTATIONS CITY OF HOPE (US) 2022-04-07 WO claimed
WO-2022063224-A1 ACTIVATED PLURIPOTENT STEM CELL, AND PREPARATION METHOD THEREFOR AND USE THEREOF 中国科学院动物研究所 2022-03-31 WO claimed
CN-114250195-A Activated pluripotent stem cell and preparation method and application thereof 中国科学院动物研究所 2022-03-29 CN claimed
CN-114209837-A Medicine for treating erectile dysfunction and application thereof 中山大学附属第五医院 2022-03-22 CN claimed
WO-2022051847-A1 METHODS FOR GENERATING NEURAL PROGENITOR CELLS WITH A SPINAL CORD IDENTITY UNIVERSITY HEALTH NETWORK (CA) 2022-03-17 WO claimed
WO-2022031952-A2 TREATMENTS FOR CANCERS HAVING KRAS MUTATIONS CITY OF HOPE (US) 2022-02-10 WO claimed
WO-2022020967-A1 USE OF WNT/BETA-CATENIN PATHWAY INHIBITORS TO BLOCK REPLICATION OF SARS-COV-2 AND OTHER PATHOGENIC VIRUSES THE GOVERNORS OF THE UNIVERSITY OF ALBERTA (CA) 2022-02-03 WO claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12570956-B2 Efficient derivation of stable pluripotent bovine embryonic stem cells WNT1, PHKA1, ACVR1 CLPP 3412/4885CTNNB1 23/4885TCF7 721/4885
US-20260125650-A1 METHODS AND COMPOSITIONS FOR GENERATING HEPATOCYTES WNT3A, GSK3B, GSK3A CLPP 3443/4885CTNNB1 8/4885TCF7 10/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.